HitPredict

Interactor 1: BUB1 (O43683)
Mitotic checkpoint serine/threonine-protein kinase BUB1 (hBUB1) (EC 2.7.11.1) (BUB1A)
Gene: BUB1

Interactor 2: ZWINT (O95229)
Outer kinetochore KNL1 complex subunit ZWINT (ZW10 interactor) (ZW10-interacting protein 1) (Zwint-1)
Gene: ZWINT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.64 0.60 0.621

The method score is based on:

Property Details
Experiments 26496610, 20360068
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000776 - kinetochore
GO:0000940 - outer kinetochore
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0007094 - mitotic spindle assembly checkpoint signaling
and 1 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 1085
Hs

1 277
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025