HitPredict

Interactor 1: DHX16 (O60231)
Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (EC 3.6.4.13) (ATP-dependent RNA helicase #3) (DEAH-box protein 16)
Gene: DHX16

Interactor 2: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35509820
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0043130 - ubiquitin binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1041 Hs			1 465
+	Hs
		227453 DHX8_HUMAN (74-1040): 0: 783: 39.96		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		228233 PRP16_HUMAN (20-1024): 0: 770: 36.77		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		195278 DHX15_HUMAN (371-1033): 0: 719: 50.22		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		224752 DHX16_HUMAN (1-1041): 0: 943: 100.00		UBC_HUMAN (1-77): 1.15e-29: 124: 32.47
+	Hs
		228704 DHX33_HUMAN (375-1019): 0: 647: 45.50		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		227990 DHX40_HUMAN (394-1036): 0: 582: 39.27		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		195296 DHX15_HUMAN (371-1033): 0: 719: 50.22		ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82
+	Hs
		475760 DHX8_HUMAN (74-1040): 0: 783: 39.96		UBC_HUMAN (1-77): 1.15e-29: 124: 32.47
+	Hs
		195327 DHX15_HUMAN (371-1033): 0: 719: 50.22		UBC_HUMAN (1-77): 1.15e-29: 124: 32.47
+	At
		1092221 DEAH2_ARATH (354-1039): 0: 705: 49.01		UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17