HitPredict

Interactor 1: MED14 (O60244)
Mediator of RNA polymerase II transcription subunit 14 (Activator-recruited cofactor 150 kDa component) (ARC150) (Cofactor required for Sp1 transcriptional activation subunit 2) (CRSP complex subunit 2) (Mediator complex subunit 14) (RGR1 homolog) (hRGR1) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150)
Gene: MED14

Interactor 2: RPB7 (P62487)
DNA-directed RNA polymerase II subunit RPB7 (RNA polymerase II subunit B7) (DNA-directed RNA polymerase II subunit G) (RNA polymerase II 19 kDa subunit) (RPB19)
Gene: POLR2G

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	24981860, 26496610, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1454 Hs			1 172
+	Sc
		581349 MED14_YEAST (2-463): 8.6e-138: 453: 18.45		RPB7_YEAST (1-171): 4.45e-63: 193: 42.78
+	Hs
		123901 SPT5H_HUMAN (1062-1272): 9.25e-11: 68.8: 14.41		RPB7_HUMAN (1-172): 1.48e-76: 227: 100.00
+	Bt
		102298 RPB1_BOVIN (1059-1159): 8.45e-09: 62.5: 23.30		RPB7_BOVIN (1-172): 1.48e-76: 227: 100.00
+	Hs
		624849 RPB1_HUMAN (1059-1159): 8.88e-09: 62.5: 23.30		RPB7_HUMAN (1-172): 1.48e-76: 227: 100.00
+	Hs
		625110 RPB1_HUMAN (1059-1159): 8.88e-09: 62.5: 23.30		RPC8_HUMAN (1-172): 5.28e-54: 171: 18.72