HitPredict

Interactor 1: MED14 (O60244)
Mediator of RNA polymerase II transcription subunit 14 (Activator-recruited cofactor 150 kDa component) (ARC150) (Cofactor required for Sp1 transcriptional activation subunit 2) (CRSP complex subunit 2) (Mediator complex subunit 14) (RGR1 homolog) (hRGR1) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150)
Gene: MED14

Interactor 2: TNR6A (Q8NDV7)
Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (EMSY interactor protein) (GW182 autoantigen) (Protein GW1) (Glycine-tryptophan protein of 182 kDa)
Gene: TNRC6A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28813667
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1454 Hs			1 1962
+	Hs
		1242646 TB182_HUMAN (945-1135): 6.75e-20: 99.2: 18.33		TNR6A_HUMAN (1-1962): 0: 896: 100.00
+	Hs
		1242603 KMT2C_HUMAN (1122-1454): 3.37e-11: 70.7: 13.26		TNR6A_HUMAN (1-1962): 0: 896: 100.00
+	Hs
		1318963 TB182_HUMAN (945-1135): 6.75e-20: 99.2: 18.33		TNR6B_HUMAN (44-1944): 3.32e-153: 521: 33.57
+	Hs
		979999 IF4G1_HUMAN (840-1368): 3.72e-09: 63.8: 10.72		TNR6C_HUMAN (35-1957): 8.26e-150: 513: 37.01
+	Hs
		124057 SPT5H_HUMAN (1062-1272): 9.25e-11: 68.8: 14.41		MINT_HUMAN (30-1804): 8.51e-28: 125: 8.46
+	Hs
		1270755 CBP_HUMAN (900-1355): 2.7e-13: 77.7: 10.70		CBP_HUMAN (735-1745): 8.61e-21: 102: 9.54
+	Hs
		554259 MUC1_HUMAN (958-1293): 3.26e-12: 73.7: 15.23		MUC1_HUMAN (845-1740): 1.98e-15: 84.9: 11.69
+	Hs
		1170076 CBP_HUMAN (900-1355): 2.7e-13: 77.7: 10.70		SRCAP_HUMAN (1139-1823): 1.12e-12: 75.9: 10.82
+	Hs
		124109 SPT5H_HUMAN (1062-1272): 9.25e-11: 68.8: 14.41		CHD7_HUMAN (1210-1768): 5.37e-15: 83.6: 12.63
+	Hs
		998940 CBP_HUMAN (900-1355): 2.7e-13: 77.7: 10.70		EP300_HUMAN (789-1765): 6.73e-09: 63.6: 9.05
+	Hs
		554303 MUC1_HUMAN (958-1293): 3.26e-12: 73.7: 15.23		EP300_HUMAN (789-1765): 6.73e-09: 63.6: 9.05
+	Mm
		1351630 PCLO_MOUSE (848-1405): 4.06e-11: 70.3: 12.13		PCLO_MOUSE (19-1290): 1.41e-09: 66: 10.73
+	Hs
		124017 SPT5H_HUMAN (1062-1272): 9.25e-11: 68.8: 14.41		ARI1B_HUMAN (551-1540): 1.58e-09: 65.5: 8.99
+	Dm
		113976 M9PB30_DROME (896-1454): 4.15e-11: 70.3: 9.90		M9PB30_DROME (58-812): 9.58e-09: 63.2: 8.52
+	Hs
		123923 SPT5H_HUMAN (1062-1272): 9.25e-11: 68.8: 14.41		EP300_HUMAN (789-1765): 6.73e-09: 63.6: 9.05
+	Hs
		999163 RERE_HUMAN (945-1199): 7.88e-10: 66: 14.60		EP300_HUMAN (789-1765): 6.73e-09: 63.6: 9.05
+	Mm
		70879 F8VPR5_MOUSE (836-1217): 4.53e-09: 63.8: 7.75		EP300_MOUSE (789-1735): 2.76e-09: 64.7: 9.79
+	Hs
		998826 SRCAP_HUMAN (853-1422): 3.36e-09: 64.2: 9.60		EP300_HUMAN (789-1765): 6.73e-09: 63.6: 9.05
+	Hs
		624875 RPB1_HUMAN (1059-1159): 8.88e-09: 62.5: 23.30		EP300_HUMAN (789-1765): 6.73e-09: 63.6: 9.05