Interactor 1: PCDH7 (O60245)
Protocadherin-7 (Brain-heart protocadherin) (BH-Pcdh)
Gene: PCDH7
Interactor 2: RET (P07949)
Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]
Gene: RET
Species: Homo sapiens
Source: biogrid
Category: High-throughput
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.38 | 1.00 | 0.618 |
The method score is based on:
Property | Details |
---|---|
Experiments | 32062451 |
Identification Methods | affinity chromatography technology |
Interaction Type | physical association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | Cadherin~Cadherin, Cadherin~RET_CLD1, Cadherin~RET_CLD3, Cadherin~RET_CLD4, Cadherin~Cadherin_2 |
Common GO terms | GO:0005509 - calcium ion binding GO:0005886 - plasma membrane GO:0007156 - homophilic cell adhesion via plasma membrane adhesion molecules |
Homologous interactions | 11 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024