Interactor 1: PCDH7 (O60245)
Protocadherin-7 (Brain-heart protocadherin) (BH-Pcdh)
Gene: PCDH7

Interactor 2: RET (P07949)
Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]
Gene: RET

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 32062451
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Cadherin~Cadherin, Cadherin~RET_CLD1, Cadherin~RET_CLD3, Cadherin~RET_CLD4, Cadherin~Cadherin_2
Common GO terms GO:0005509 - calcium ion binding
GO:0005886 - plasma membrane
GO:0007156 - homophilic cell adhesion via plasma membrane adhesion molecules
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 1069
Hs

1 1114
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Last updated: 15 Jul 2024