HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: HNRC1 (O60812)
Heterogeneous nuclear ribonucleoprotein C-like 1 (hnRNP C-like-1) (hnRNP core protein C-like 1)
Gene: HNRNPCL1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24244333
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 293
+	Hs
		226292 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		HNRPC_HUMAN (1-293): 1.35e-86: 262: 86.93
+	Hs
		227922 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		RALYL_HUMAN (2-271): 1.26e-72: 226: 48.44
+	Hs
		229027 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		RALY_HUMAN (2-280): 2.93e-66: 210: 40.33
+	Hs
		432800 CUL9_HUMAN (30-463): 1.19e-80: 274: 18.58		HNRPC_HUMAN (1-293): 1.35e-86: 262: 86.93
+	Hs
		241253 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		HNRC1_HUMAN (1-293): 1.3e-98: 293: 100.00
+	Hs
		227110 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		TRA2B_HUMAN (25-151): 2.98e-21: 92.7: 23.08
+	Hs
		228568 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		RBM4_HUMAN (17-92): 1e-16: 81.1: 19.74
+	Hs
		1219393 CUL9_HUMAN (30-463): 1.19e-80: 274: 18.58		RALY_HUMAN (2-280): 2.93e-66: 210: 40.33
+	Hs
		228408 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		RBM14_HUMAN (17-116): 2.2e-12: 69.2: 19.80
+	Hs
		432519 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		HNRPC_HUMAN (1-293): 1.35e-86: 262: 86.93
+	Hs
		312562 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		TRA2B_HUMAN (25-151): 2.98e-21: 92.7: 23.08
+	At
		955330 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		RS40_ARATH (14-272): 7.04e-36: 133: 18.01
+	At
		1091836 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		RSZ33_ARATH (8-109): 2.92e-18: 84.6: 21.57
+	At
		1092088 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		RSZ32_ARATH (8-121): 7.66e-18: 83.4: 20.51