HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: PLSL (P13796)
Plastin-2 (L-plastin) (LC64P) (Lymphocyte cytosolic protein 1) (LCP-1)
Gene: LCP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35987950
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 627
+	Hs
		226402 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PLST_HUMAN (1-627): 0: 646: 79.90
+	Hs
		227506 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PLEC_HUMAN (382-627): 4.56e-60: 219: 20.78
+	Hs
		164537 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		SPTN2_HUMAN (381-625): 7.03e-57: 210: 24.61
+	Hs
		211433 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ACTN4_HUMAN (378-625): 1.11e-56: 208: 20.23
+	Hs
		226387 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ACTN1_HUMAN (392-625): 4.81e-57: 208: 21.81
+	Hs
		227192 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		SPTB2_HUMAN (381-625): 5.99e-55: 204: 24.61
+	Hs
		475789 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		PLEC_HUMAN (382-627): 4.56e-60: 219: 20.78
+	Hs
		476576 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		MACF1_HUMAN (379-627): 4.13e-59: 217: 20.62