Protein: AA2AR
Adenosine receptor A2a

Gene: AA2AR, ADORA2A
Organism: Homo sapiens
Interactions: 29
UniProt ID: P29274

Gene Ontology (top 5):
GO:0001609 - G protein-coupled adenosine receptor activity
GO:0001963 - synaptic transmission, dopaminergic
GO:0001973 - G protein-coupled adenosine receptor signaling pathway
GO:0001975 - response to amphetamine
GO:0005516 - calmodulin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

709238

AA2AR
Adenosine receptor A2a

5

15

Small-scale

0.909

High

186886

GPR37
Prosaposin receptor GPR37

1

17

High-throughput

0.772

High

638880

CNR1
Cannabinoid receptor 1

2

18

Small-scale

0.768

High

572413

DRD2
D(2) dopamine receptor

1

19

Small-scale

0.724

High

709256

HRH3
Histamine H3 receptor

1

20

Small-scale

0.724

High

709251

NECA2
N-terminal EF-hand calcium-binding protein 2

2

1

Small-scale

0.639

High

709239

AA2BR
Adenosine receptor A2b

1

18

Small-scale

0.618

High

709240

AA1R
Adenosine receptor A1

1

16

Small-scale

0.618

High

179821

BET1
BET1 homolog

2

1

High-throughput

0.606

High

226308

SNG1
Synaptogyrin-1

2

3

High-throughput

0.606

High

709248

WLS
Protein wntless homolog

2

2

Small-scale

0.601

High

709252

CYH2
Cytohesin-2

1

1

Small-scale

0.586

High

709245

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

5

Small-scale

0.523

High

709253

NADAP
Kanadaptin

1

0

High-throughput

0.518

High

709255

SPNS1
Protein spinster homolog 1

1

0

High-throughput

0.518

High

378836

CD4
T-cell surface glycoprotein CD4

1

1

Small-scale

0.501

High

539117

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

1

1

High-throughput

0.494

High

586974

CHIN
N-chimaerin

1

3

High-throughput

0.494

High

709241

HNRH3
Heterogeneous nuclear ribonucleoprotein H3

1

3

High-throughput

0.494

High

709247

PPM1J
Protein phosphatase 1J

1

1

High-throughput

0.494

High

709249

RHBD2
Rhomboid domain-containing protein 2

1

2

High-throughput

0.494

High

709254

S2539
Mitochondrial glutathione transporter SLC25A39

1

9

High-throughput

0.494

High

709244

NAMPT
Nicotinamide phosphoribosyltransferase

1

0

Small-scale

0.486

High

709242

SYUA
Alpha-synuclein

1

3

High-throughput

0.481

High

709243

GRM5
Metabotropic glutamate receptor 5

1

6

Small-scale

0.479

High

709246

TNIP1
TNFAIP3-interacting protein 1

1

1

High-throughput

0.479

High

366672

ADA
Adenosine deaminase

1

0

Small-scale

0.458

High

709250

POZP3
POM121 and ZP3 fusion protein

1

0

High-throughput

0.282

High


Service provided by Combinatics, Japan

Last updated: 11Aug2025