HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: HNRPL (P14866)
Heterogeneous nuclear ribonucleoprotein L (hnRNP L)
Gene: HNRNPL

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35509820, 35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 589
+	Hs
		228185 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		HNRLL_HUMAN (31-587): 2.07e-86: 280: 48.93
+	Hs
		226766 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		MATR3_HUMAN (71-364): 1.41e-59: 214: 20.64
+	Hs
		227642 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PAP1L_HUMAN (53-399): 1.07e-43: 166: 16.62
+	Hs
		226375 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PABP1_HUMAN (53-384): 1.89e-42: 163: 16.19
+	Hs
		227354 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PABP4_HUMAN (53-368): 1.3e-41: 161: 15.48
+	Hs
		228678 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PABP3_HUMAN (53-474): 1.68e-38: 152: 15.16
+	Hs
		226575 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PTBP1_HUMAN (20-270): 3.87e-26: 114: 18.73
+	Hs
		226164 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PTBP3_HUMAN (27-270): 2.6e-21: 99.7: 17.88
+	Hs
		229022 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PTBP2_HUMAN (42-270): 4.52e-17: 86.3: 14.90
+	Hs
		475300 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		HNRPL_HUMAN (1-589): 5.72e-115: 356: 100.00
+	Hs
		1031383 CUL9_HUMAN (30-463): 1.19e-80: 274: 18.58		PABP4_HUMAN (53-368): 1.3e-41: 161: 15.48
+	Hs
		312462 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		PABP1_HUMAN (53-384): 1.89e-42: 163: 16.19
+	Hs
		475456 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		MATR3_HUMAN (71-364): 1.41e-59: 214: 20.64
+	Hs
		475288 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		PABP1_HUMAN (53-384): 1.89e-42: 163: 16.19
+	Hs
		475708 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		PABP4_HUMAN (53-368): 1.3e-41: 161: 15.48
+	Hs
		475363 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		PTBP1_HUMAN (20-270): 3.87e-26: 114: 18.73
+	At
		1091716 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		PTBP3_ARATH (47-268): 1.26e-15: 81.2: 17.93