Protein: GPR42
G-protein coupled receptor 42

Gene: GPR42
Organism: Homo sapiens
Interactions: 101
UniProt ID: O15529

Gene Ontology (top 5):
GO:0004930 - G protein-coupled receptor activity
GO:0005886 - plasma membrane
GO:0007186 - G protein-coupled receptor signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

193379

G37L1
G-protein coupled receptor 37-like 1

1

17

High-throughput

0.665

High

193407

CXCL9
C-X-C motif chemokine 9

1

1

High-throughput

0.665

High

193432

BT2A2
Butyrophilin subfamily 2 member A2

1

1

High-throughput

0.665

High

193408

CLM6
CMRF35-like molecule 6

1

0

High-throughput

0.630

High

193430

CC4L
C-C motif chemokine 4-like

1

20

High-throughput

0.594

High

154518

PLPP1
Phospholipid phosphatase 1

1

2

High-throughput

0.515

High

193376

MGA
Maltase-glucoamylase

1

2

High-throughput

0.515

High

193377

LAT
Linker for activation of T-cells family member 1

1

3

High-throughput

0.515

High

193378

SNG1
Synaptogyrin-1

1

4

High-throughput

0.515

High

193383

TRFE
Serotransferrin

1

2

High-throughput

0.515

High

193385

GLPC
Glycophorin-C

1

1

High-throughput

0.515

High

193389

ITAM
Integrin alpha-M

1

3

High-throughput

0.515

High

193391

CD79A
B-cell antigen receptor complex-associated protein alpha chain

1

2

High-throughput

0.515

High

193393

COMT
Catechol O-methyltransferase

1

1

High-throughput

0.515

High

193395

VATL
V-type proton ATPase 16 kDa proteolipid subunit c

1

4

High-throughput

0.515

High

193396

CXB2
Gap junction beta-2 protein

1

12

High-throughput

0.515

High

193399

ATP4B
Potassium-transporting ATPase subunit beta

1

6

High-throughput

0.515

High

193400

EFNA5
Ephrin-A5

1

5

High-throughput

0.515

High

193402

EMP1
Epithelial membrane protein 1

1

8

High-throughput

0.515

High

193403

BI1
Bax inhibitor 1

1

8

High-throughput

0.515

High

193404

MYPR
Myelin proteolipid protein

1

4

High-throughput

0.515

High

193405

PMP22
Peripheral myelin protein 22

1

8

High-throughput

0.515

High

193406

ILRL1
Interleukin-1 receptor-like 1

1

4

High-throughput

0.515

High

193409

KCNA1
Potassium voltage-gated channel subfamily A member 1

1

7

High-throughput

0.515

High

193411

FXYD3
FXYD domain-containing ion transport regulator 3

1

3

High-throughput

0.515

High

193416

RTP2
Receptor-transporting protein 2

1

4

High-throughput

0.515

High

193417

TSPO2
Translocator protein 2

1

2

High-throughput

0.515

High

193419

MFSD5
Molybdate-anion transporter

1

3

High-throughput

0.515

High

193425

S41A1
Solute carrier family 41 member 1

1

5

High-throughput

0.515

High

193426

ZNT8
Proton-coupled zinc antiporter SLC30A8

1

19

High-throughput

0.515

High

193431

LHPL5
LHFPL tetraspan subfamily member 5 protein

1

1

High-throughput

0.515

High

193435

KLRG1
Killer cell lectin-like receptor subfamily G member 1

1

6

High-throughput

0.515

High

193439

S41A2
Solute carrier family 41 member 2

1

5

High-throughput

0.515

High

193440

TM237
Transmembrane protein 237

1

1

High-throughput

0.515

High

193441

VATO
V-type proton ATPase 21 kDa proteolipid subunit c''

1

4

High-throughput

0.515

High

193442

ZNT3
Probable proton-coupled zinc antiporter SLC30A3

1

19

High-throughput

0.515

High

193443

ZNT2
Proton-coupled zinc antiporter SLC30A2

1

19

High-throughput

0.515

High

193444

YIPF4
Protein YIPF4

1

11

High-throughput

0.515

High

193445

TM147
BOS complex subunit TMEM147

1

1

High-throughput

0.515

High

193448

FXYD6
FXYD domain-containing ion transport regulator 6

1

3

High-throughput

0.515

High

193449

S38A1
Sodium-coupled neutral amino acid symporter 1

1

8

High-throughput

0.515

High

193451

SYNG1
Synapse differentiation-inducing gene protein 1

1

11

High-throughput

0.515

High

193453

JPH1
Junctophilin-1

1

3

High-throughput

0.515

High

193454

S39A2
Zinc transporter ZIP2

1

20

High-throughput

0.515

High

193456

SERC1
Serine incorporator 1

1

7

High-throughput

0.515

High

193465

CLC2D
C-type lectin domain family 2 member D

1

5

High-throughput

0.515

High

193466

LCAP
Leucyl-cystinyl aminopeptidase

1

8

High-throughput

0.515

High

193467

STX8
Syntaxin-8

1

3

High-throughput

0.515

High

193468

YIPF1
Protein YIPF1

1

15

High-throughput

0.515

High

193390

CD20
B-lymphocyte antigen CD20

1

0

High-throughput

0.493

High

193414

CC50B
Cell cycle control protein 50B

1

0

High-throughput

0.493

High

193420

TMM65
Transmembrane protein 65

1

0

High-throughput

0.493

High

193421

TM182
Transmembrane protein 182

1

0

High-throughput

0.493

High

193422

MFSD6
Major facilitator superfamily domain-containing protein 6

1

0

High-throughput

0.493

High

193463

NINJ2
Ninjurin-2

1

0

High-throughput

0.493

High

63623

A5PKU2
TUSC5 protein

1

8

High-throughput

0.470

High

97167

TM262
Cation channel sperm-associated auxiliary subunit TMEM262

1

1

High-throughput

0.470

High

160225

GOSR2
Golgi SNAP receptor complex member 2

1

1

High-throughput

0.470

High

193380

YIF1A
Protein YIF1A

1

8

High-throughput

0.470

High

193381

ZFPL1
Zinc finger protein-like 1

1

1

High-throughput

0.470

High

193382

LERL1
Leptin receptor overlapping transcript-like 1

1

1

High-throughput

0.470

High

193386

APOD
Apolipoprotein D

1

5

High-throughput

0.470

High

193387

PAEP
Glycodelin

1

4

High-throughput

0.470

High

193392

AL5AP
Arachidonate 5-lipoxygenase-activating protein

1

4

High-throughput

0.470

High

193394

IBP5
Insulin-like growth factor-binding protein 5

1

5

High-throughput

0.470

High

193397

NSG1
Neuronal vesicle trafficking-associated protein 1

1

2

High-throughput

0.470

High

193398

T4S4
Transmembrane 4 L6 family member 4

1

2

High-throughput

0.470

High

193401

LIPR1
Inactive pancreatic lipase-related protein 1

1

1

High-throughput

0.470

High

193410

BNIP3
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3

1

2

High-throughput

0.470

High

193412

ADIPO
Adiponectin

1

5

High-throughput

0.470

High

193413

LTC4S
Leukotriene C4 synthase

1

4

High-throughput

0.470

High

193415

CTXN3
Cortexin-3

1

3

High-throughput

0.470

High

193418

S35E4
Solute carrier family 35 member E4

1

2

High-throughput

0.470

High

193423

ERMP1
Endoplasmic reticulum metallopeptidase 1

1

9

High-throughput

0.470

High

193424

ANR46
Ankyrin repeat domain-containing protein 46

1

9

High-throughput

0.470

High

193427

NRM
Nurim

1

1

High-throughput

0.470

High

193429

SERP2
Stress-associated endoplasmic reticulum protein 2

1

2

High-throughput

0.470

High

193433

TM239
Transmembrane protein 239

1

1

High-throughput

0.470

High

193434

FAM3C
Protein FAM3C

1

3

High-throughput

0.470

High

193436

YIPF6
Protein YIPF6

1

11

High-throughput

0.470

High

193437

RUSF1
RUS family member 1

1

7

High-throughput

0.470

High

193446

YIPF2
Protein YIPF2

1

15

High-throughput

0.470

High

193447

SMIM3
Small integral membrane protein 3

1

1

High-throughput

0.470

High

193450

TMM60
Transmembrane protein 60

1

1

High-throughput

0.470

High

193452

AT131
Endoplasmic reticulum transmembrane helix translocase

1

20

High-throughput

0.470

High

193455

SMCO4
Single-pass membrane and coiled-coil domain-containing protein 4

1

1

High-throughput

0.470

High

193457

RPRM
Protein reprimo

1

4

High-throughput

0.470

High

193458

TREX1
Three-prime repair exonuclease 1

1

2

High-throughput

0.470

High

193460

S38A7
Sodium-coupled neutral amino acid transporter 7

1

8

High-throughput

0.470

High

193462

NDUBB
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial

1

1

High-throughput

0.470

High

193464

CC167
Coiled-coil domain-containing protein 167

1

2

High-throughput

0.470

High

193470

TX264
Testis-expressed protein 264

1

3

High-throughput

0.470

High

58642

SRTM1
Serine-rich and transmembrane domain-containing protein 1

1

0

High-throughput

0.268

Low

144380

SCD
Stearoyl-CoA desaturase

1

0

High-throughput

0.268

Low

193384

STAT
Statherin

1

0

High-throughput

0.268

Low

193388

DWORF
Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator DWORF

1

0

High-throughput

0.268

Low

193428

DRAM1
DNA damage-regulated autophagy modulator protein 1

1

0

High-throughput

0.268

Low

193438

TMM19
Transmembrane protein 19

1

0

High-throughput

0.268

Low

193459

TM140
Transmembrane protein 140

1

0

High-throughput

0.268

Low

193461

TM242
Transmembrane protein 242

1

0

High-throughput

0.268

Low

193469

IR3IP
Immediate early response 3-interacting protein 1

1

0

High-throughput

0.268

Low


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Last updated: 11Aug2025