Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: NSF (P46459)
Vesicle-fusing ATPase (EC 3.6.4.6) (N-ethylmaleimide-sensitive fusion protein) (NEM-sensitive fusion protein) (Vesicular-fusion protein NSF)
Gene: NSF

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 35509820, 35256949
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA~ubiquitin
Common GO terms GO:0005794 - Golgi apparatus
GO:0005829 - cytosol
GO:0014069 - postsynaptic density
GO:0019901 - protein kinase binding
GO:0030165 - PDZ domain binding
and 2 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 465
Hs

1 744
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Last updated: 15 Jul 2024