HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: VIGLN (Q00341)
Vigilin (High density lipoprotein-binding protein) (HDL-binding protein)
Gene: HDLBP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.683

Property	Details
Experiments	30021884, 35509820, 35987950, 35256949
Identification Methods	proximity labelling technology, affinity chromatography technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 1268
+	Hs
		228358 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		FUBP3_HUMAN (796-1122): 1.09e-33: 140: 16.85
+	Hs
		228262 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		FUBP2_HUMAN (227-575): 5.22e-28: 123: 13.06
+	Hs
		228295 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		FUBP1_HUMAN (641-950): 1.47e-27: 121: 14.21
+	Hs
		127952 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		IF2B3_HUMAN (23-228): 7.78e-25: 113: 15.70
+	Hs
		227521 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PCBP2_HUMAN (968-1137): 1.24e-22: 103: 20.57
+	Hs
		228921 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		IF2B1_HUMAN (58-368): 1.59e-20: 99.6: 15.52
+	Hs
		229223 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		IF2B2_HUMAN (920-1124): 2.37e-18: 92.7: 14.76
+	Hs
		227520 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PCBP1_HUMAN (1128-1232): 3.39e-10: 65.3: 16.19
+	Hs
		1072089 ARI1_HUMAN (163-464): 3.95e-74: 244: 19.67		PCBP1_HUMAN (1128-1232): 3.39e-10: 65.3: 16.19
+	Hs
		476143 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		FUBP2_HUMAN (227-575): 5.22e-28: 123: 13.06
+	Hs
		128003 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		IF2B3_HUMAN (23-228): 7.78e-25: 113: 15.70
+	Hs
		475796 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		PCBP2_HUMAN (968-1137): 1.24e-22: 103: 20.57