HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: HNRPU (Q00839)
Heterogeneous nuclear ribonucleoprotein U (hnRNP U) (GRIP120) (Nuclear p120 ribonucleoprotein) (Scaffold-attachment factor A) (SAF-A) (p120) (pp120)
Gene: HNRNPU

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.76 0.60 0.676

The method score is based on:

Property Details
Experiments 32929329, 35509820, 35256949, 24244333
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003714 - transcription corepressor activity
GO:0003779 - actin binding
GO:0005634 - nucleus
GO:0005829 - cytosol
and 3 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 465
Hs

1 825
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024