HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: CAF1B (Q13112)
Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-I p60) (M-phase phosphoprotein 7)
Gene: CHAF1B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35509820, 35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 559
+	Hs
		228555 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		KTNB1_HUMAN (59-549): 3.11e-36: 145: 16.60
+	Hs
		226765 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		LIS1_HUMAN (222-474): 9.92e-34: 134: 8.81
+	Hs
		228612 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		TBL1R_HUMAN (211-422): 1.4e-24: 109: 7.93
+	Hs
		227292 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		TBL3_HUMAN (11-372): 1.78e-20: 97.6: 16.59
+	Hs
		228868 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		NLE1_HUMAN (329-440): 1.36e-17: 87.8: 10.71
+	Hs
		227054 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		WDR5_HUMAN (2-94): 9.73e-14: 74.3: 24.21
+	Hs
		226098 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		CIAO1_HUMAN (163-380): 1.14e-13: 74.1: 15.77
+	Hs
		228623 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		WDR33_HUMAN (229-385): 7.81e-13: 73.7: 14.84
+	Sc
		477393 UBI4P_YEAST (1-229): 3.48e-61: 205: 18.72		COPA_YEAST (162-426): 2.1e-28: 122: 6.83
+	Sc
		477447 UBI4P_YEAST (1-229): 3.48e-61: 205: 18.72		CIAO1_YEAST (13-198): 1.04e-12: 71.2: 24.74
+	Hs
		475563 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		WDR5_HUMAN (2-94): 9.73e-14: 74.3: 24.21
+	Hs
		282808 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		CIAO1_HUMAN (163-380): 1.14e-13: 74.1: 15.77
+	Hs
		476334 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		WDR33_HUMAN (229-385): 7.81e-13: 73.7: 14.84