HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: ACSM3 (Q53FZ2)
Acyl-coenzyme A synthetase ACSM3, mitochondrial (EC 6.2.1.2) (Acyl-CoA synthetase medium-chain family member 3) (Butyrate--CoA ligase 3) (Butyryl-coenzyme A synthetase 3) (Middle-chain acyl-CoA synthetase 3) (Propionate--CoA ligase) (EC 6.2.1.17) (Protein SA homolog)
Gene: ACSM3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 586
+	Hs
		228801 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ACSA_HUMAN (23-580): 1.52e-165: 489: 24.64
+	Hs
		228304 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ACSF2_HUMAN (70-584): 4.78e-149: 444: 22.55
+	Sc
		477375 UBI4P_YEAST (1-229): 3.48e-61: 205: 18.72		ACS2_YEAST (27-580): 3.67e-160: 475: 24.50
+	At
		82601 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		ACS_ARATH (32-580): 6.95e-174: 512: 26.15
+	At
		1092362 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		4CLLA_ARATH (69-584): 4.98e-149: 440: 22.46
+	Hs
		227637 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ACSF3_HUMAN (94-578): 1.02e-30: 128: 25.60