HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: PAP1M (Q5JQF8)
Polyadenylate-binding protein 1-like 2 (RNA-binding motif protein 32) (RNA-binding protein 32)
Gene: PABPC1L2A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 200
+	Hs
		227642 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PAP1L_HUMAN (3-172): 3.05e-51: 175: 29.03
+	Hs
		228318 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PABP5_HUMAN (3-169): 9.13e-45: 154: 25.14
+	Hs
		226375 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PABP1_HUMAN (80-198): 5.59e-24: 100: 23.14
+	Hs
		227354 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PABP4_HUMAN (87-198): 6.25e-24: 100: 22.81
+	Hs
		227533 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		SF3B4_HUMAN (91-198): 1.51e-24: 100: 20.91
+	Hs
		228678 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PABP3_HUMAN (80-198): 3.53e-22: 95.2: 21.49
+	Hs
		1031383 CUL9_HUMAN (30-463): 1.19e-80: 274: 18.58		PABP4_HUMAN (87-198): 6.25e-24: 100: 22.81
+	Hs
		312462 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		PABP1_HUMAN (80-198): 5.59e-24: 100: 23.14
+	Hs
		475288 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		PABP1_HUMAN (80-198): 5.59e-24: 100: 23.14
+	Hs
		475708 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		PABP4_HUMAN (87-198): 6.25e-24: 100: 22.81
+	At
		186465 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		PABP4_ARATH (90-200): 2.5e-23: 98.6: 19.47
+	At
		983451 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		PABP5_ARATH (85-200): 2.1e-21: 92.9: 16.24