HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: ELP2 (Q6IA86)
Elongator complex protein 2 (ELP2) (SHINC-2) (STAT3-interacting protein 1) (StIP1)
Gene: ELP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35509820
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0019901 - protein kinase binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 826
+	Hs
		152845 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		APAF_HUMAN (312-822): 5.88e-63: 232: 14.46
+	Hs
		228868 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		NLE1_HUMAN (467-826): 1.07e-51: 190: 12.56
+	Hs
		229068 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		WDR3_HUMAN (5-281): 5.06e-37: 152: 14.19
+	Hs
		226765 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		LIS1_HUMAN (384-752): 5.32e-38: 148: 11.54
+	Hs
		227292 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		TBL3_HUMAN (2-142): 4.37e-26: 116: 23.40
+	Hs
		226026 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		WDR1_HUMAN (7-254): 2.09e-15: 82.2: 14.29
+	Hs
		228157 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		GEMI5_HUMAN (652-825): 8.05e-15: 81.3: 10.57
+	Hs
		228612 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		TBL1R_HUMAN (382-696): 4.63e-11: 68: 17.80
+	Hs
		226098 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		CIAO1_HUMAN (565-792): 8.89e-09: 59.9: 17.80
+	At
		1092114 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		Q9LHN3_ARATH (195-416): 4.46e-11: 68.7: 18.88
+	Hs
		282808 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		CIAO1_HUMAN (565-792): 8.89e-09: 59.9: 17.80