Protein: GBG8
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 (Gamma-9)

Gene: GBG8, GNG8
Organism: Homo sapiens
Interactions: 124
UniProt ID: Q9UK08

Gene Ontology (top 5):
GO:0003924 - GTPase activity
GO:0005834 - heterotrimeric G-protein complex
GO:0005886 - plasma membrane
GO:0007186 - G protein-coupled receptor signaling pathway
GO:0031681 - G-protein beta-subunit binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

921079

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

2

20

Small-scale

0.799

High

1334924

GBB4
Guanine nucleotide-binding protein subunit beta-4

2

20

Small-scale

0.799

High

560895

GBB3
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3

1

20

Small-scale

0.724

High

154700

GNB5
Guanine nucleotide-binding protein subunit beta-5

1

20

High-throughput

0.691

High

353476

PIGR
Polymeric immunoglobulin receptor

1

0

High-throughput

0.656

High

678316

COR1A
Coronin-1A

1

0

High-throughput

0.656

High

921771

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

20

Small-scale

0.618

High

119875

RB27B
Ras-related protein Rab-27B

1

1

High-throughput

0.536

High

341597

CFAB
Complement factor B

1

1

High-throughput

0.536

High

344132

ANT3
Antithrombin-III

1

3

High-throughput

0.536

High

344723

CO3
Complement C3

1

2

High-throughput

0.536

High

361410

APOA1
Apolipoprotein A-I

1

1

High-throughput

0.536

High

361790

FIBA
Fibrinogen alpha chain [Cleaved into: Fibrinopeptide A; Fibrinogen alpha chain]

1

3

High-throughput

0.536

High

361946

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

1

3

High-throughput

0.536

High

362040

FIBG
Fibrinogen gamma chain

1

3

High-throughput

0.536

High

362642

APOH
Beta-2-glycoprotein 1

1

3

High-throughput

0.536

High

363339

FINC
Fibronectin

1

1

High-throughput

0.536

High

364625

TRFE
Serotransferrin

1

1

High-throughput

0.536

High

364754

TRFL
Lactotransferrin

1

1

High-throughput

0.536

High

372968

C4BPA
C4b-binding protein alpha chain

1

4

High-throughput

0.536

High

376332

ANXA1
Annexin A1

1

1

High-throughput

0.536

High

378857

HRG
Histidine-rich glycoprotein

1

1

High-throughput

0.536

High

391482

GNAI2
Guanine nucleotide-binding protein G(i) subunit alpha-2

1

20

High-throughput

0.536

High

416726

S10A6
Protein S100-A6

1

1

High-throughput

0.536

High

439374

CATG
Cathepsin G

1

5

High-throughput

0.536

High

451049

GNAO

1

20

High-throughput

0.536

High

475231

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

3

High-throughput

0.536

High

506143

ITAM
Integrin alpha-M

1

1

High-throughput

0.536

High

519703

ANXA3
Annexin A3

1

1

High-throughput

0.536

High

533255

PLSL
Plastin-2

1

1

High-throughput

0.536

High

580458

GNAZ
Guanine nucleotide-binding protein G(z) subunit alpha

1

20

High-throughput

0.536

High

621824

PRTN3
Myeloblastin

1

6

High-throughput

0.536

High

670493

GNA11
Guanine nucleotide-binding protein subunit alpha-11

1

20

High-throughput

0.536

High

837664

GNAQ
Guanine nucleotide-binding protein G(q) subunit alpha

1

20

High-throughput

0.536

High

926724

GNAI1
Guanine nucleotide-binding protein G(i) subunit alpha-1

1

20

High-throughput

0.536

High

1053453

GNA13
Guanine nucleotide-binding protein subunit alpha-13

1

20

High-throughput

0.536

High

1056186

ITIH4
Inter-alpha-trypsin inhibitor heavy chain H4

1

2

High-throughput

0.536

High

1318835

FTO
Alpha-ketoglutarate-dependent dioxygenase FTO

1

2

High-throughput

0.536

High

1335870

MUC5B
Mucin-5B

1

3

High-throughput

0.536

High

687040

CXCR5
C-X-C chemokine receptor type 5

1

1

Small-scale

0.515

High

336795

CERU
Ceruloplasmin

1

0

High-throughput

0.513

High

341406

PLMN
Plasminogen

1

0

High-throughput

0.513

High

376518

APOB
Apolipoprotein B-100

1

0

High-throughput

0.513

High

389797

CY24B
Cytochrome b-245 heavy chain

1

0

High-throughput

0.513

High

396656

ITB2
Integrin beta-2

1

0

High-throughput

0.513

High

414107

GELS
Gelsolin

1

0

High-throughput

0.513

High

659648

GRAN
Grancalcin

1

0

High-throughput

0.513

High

854860

GDIR2
Rho GDP-dissociation inhibitor 2

1

0

High-throughput

0.513

High

1114257

TBB8
Tubulin beta-8 chain

1

0

High-throughput

0.513

High

1166187

OLFM4
Olfactomedin-4

1

0

High-throughput

0.513

High

1239880

GOLM1
Golgi membrane protein 1

1

0

High-throughput

0.513

High

1287943

PAUF
Pancreatic adenocarcinoma up-regulated factor

1

0

High-throughput

0.513

High

60442

POTEF
POTE ankyrin domain family member F

1

1

High-throughput

0.489

High

68209

F1712
Protein FAM171A2

1

1

High-throughput

0.489

High

82469

IGLL5
Immunoglobulin lambda-like polypeptide 5

1

6

High-throughput

0.489

High

334377

AL1A1
Aldehyde dehydrogenase 1A1

1

1

High-throughput

0.489

High

341250

HPT
Haptoglobin

1

3

High-throughput

0.489

High

341267

HPTR
Haptoglobin-related protein

1

2

High-throughput

0.489

High

344249

A1AT
Alpha-1-antitrypsin

1

3

High-throughput

0.489

High

344348

AACT
Alpha-1-antichymotrypsin

1

3

High-throughput

0.489

High

344587

A2MG
Alpha-2-macroglobulin

1

2

High-throughput

0.489

High

362564

C1QB
Complement C1q subcomponent subunit B

1

2

High-throughput

0.489

High

363465

A1AG1
Alpha-1-acid glycoprotein 1

1

1

High-throughput

0.489

High

363543

FETUA
Alpha-2-HS-glycoprotein

1

1

High-throughput

0.489

High

363940

ALBU
Albumin

1

1

High-throughput

0.489

High

364030

VTDB
Vitamin D-binding protein

1

1

High-throughput

0.489

High

364812

HEMO
Hemopexin

1

3

High-throughput

0.489

High

373085

VTNC
Vitronectin

1

3

High-throughput

0.489

High

397702

IC1
Plasma protease C1 inhibitor

1

4

High-throughput

0.489

High

434678

TSP1
Thrombospondin-1

1

1

High-throughput

0.489

High

439095

ELNE
Neutrophil elastase

1

5

High-throughput

0.489

High

441790

CFAH
Complement factor H

1

3

High-throughput

0.489

High

540443

MMP9
Matrix metalloproteinase-9

1

3

High-throughput

0.489

High

566119

BPI
Bactericidal permeability-increasing protein

1

2

High-throughput

0.489

High

586106

A1AG2
Alpha-1-acid glycoprotein 2

1

1

High-throughput

0.489

High

587383

ITIH2
Inter-alpha-trypsin inhibitor heavy chain H2

1

2

High-throughput

0.489

High

587407

ITIH1
Inter-alpha-trypsin inhibitor heavy chain H1

1

2

High-throughput

0.489

High

612143

MMP8
Neutrophil collagenase

1

3

High-throughput

0.489

High

639119

S100P
Protein S100-P

1

1

High-throughput

0.489

High

675662

ILEU
Leukocyte elastase inhibitor

1

3

High-throughput

0.489

High

814393

AL1A3
Retinaldehyde dehydrogenase 3

1

1

High-throughput

0.489

High

1057250

KCTD2
BTB/POZ domain-containing protein KCTD2

1

11

High-throughput

0.489

High

1233590

BPIB2
BPI fold-containing family B member 2

1

2

High-throughput

0.489

High

1235390

KCD17
BTB/POZ domain-containing protein KCTD17

1

9

High-throughput

0.489

High

1255095

BPIB1
BPI fold-containing family B member 1

1

3

High-throughput

0.489

High

1272055

RAD50
DNA repair protein RAD50

1

1

High-throughput

0.489

High

1342277

BPIA1
BPI fold-containing family A member 1

1

1

High-throughput

0.489

High

1356227

DD19B
ATP-dependent RNA helicase DDX19B

1

1

High-throughput

0.489

High

1356229

FCGBP
IgGFc-binding protein

1

2

High-throughput

0.489

High

926657

GNAS2
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short

1

20

High-throughput

0.479

High

353569

IGKC
Immunoglobulin kappa constant

1

6

High-throughput

0.445

High

353741

IGHG1
Immunoglobulin heavy constant gamma 1

1

8

High-throughput

0.445

High

353830

IGHG2
Immunoglobulin heavy constant gamma 2

1

8

High-throughput

0.445

High

353865

IGHG3
Immunoglobulin heavy constant gamma 3

1

8

High-throughput

0.445

High

354005

IGHM
Immunoglobulin heavy constant mu

1

6

High-throughput

0.445

High

354139

IGHA1
Immunoglobulin heavy constant alpha 1

1

7

High-throughput

0.445

High

354203

IGHA2
Immunoglobulin heavy constant alpha 2

1

8

High-throughput

0.445

High

469912

CO4B
Complement C4-B

1

2

High-throughput

0.445

High

957261

MUC5A
Mucin-5AC

1

2

High-throughput

0.445

High

314926

GNAS3
Neuroendocrine secretory protein 55

1

6

High-throughput

0.407

High

416908

APOA4
Apolipoprotein A-IV

1

1

High-throughput

0.407

High

353158

IGJ
Immunoglobulin J chain

1

0

High-throughput

0.279

Low

361623

APOA2
Apolipoprotein A-II

1

0

High-throughput

0.279

Low

362440

SAMP
Serum amyloid P-component

1

0

High-throughput

0.279

Low

363660

TTHY
Transthyretin

1

0

High-throughput

0.279

Low

398213

PERM
Myeloperoxidase

1

0

High-throughput

0.279

Low

500912

CLUS
Clusterin

1

0

High-throughput

0.279

Low

559286

H15
Histone H1.5

1

0

High-throughput

0.279

Low

589124

TCO1
Transcobalamin-1

1

0

High-throughput

0.279

Low

629196

ZA2G
Zinc-alpha-2-glycoprotein

1

0

High-throughput

0.279

Low

781852

MNDA
Myeloid cell nuclear differentiation antigen

1

0

High-throughput

0.279

Low

837106

MRE11
Double-strand break repair protein MRE11

1

0

High-throughput

0.279

Low

856286

HXK3
Hexokinase-3

1

0

High-throughput

0.279

Low

901628

LYSC
Lysozyme C

1

0

High-throughput

0.279

Low

935842

HBB
Hemoglobin subunit beta

1

0

High-throughput

0.279

Low

945759

NGAL
Neutrophil gelatinase-associated lipocalin

1

0

High-throughput

0.279

Low

1050462

DPOA2
DNA polymerase alpha subunit B

1

0

High-throughput

0.279

Low

1081810

PROL4
Proline-rich protein 4

1

0

High-throughput

0.279

Low

1160102

LEG1H
Protein LEG1 homolog

1

0

High-throughput

0.279

Low

1302604

INT14
Integrator complex subunit 14

1

0

High-throughput

0.279

Low

1347570

UCKL1
Uridine-cytidine kinase-like 1

1

0

High-throughput

0.279

Low

1355137

DMBT1
Deleted in malignant brain tumors 1 protein

1

0

High-throughput

0.279

Low

1356226

PADI4
Protein-arginine deiminase type-4

1

0

High-throughput

0.279

Low

1356228

EXOG
Nuclease EXOG, mitochondrial

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024