Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: SIAH3 (Q8IW03)
Seven in absentia homolog 3 (Siah-3)
Gene: SIAH3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 0.55 0.458

The method score is based on:

Property Details
Experiments 35256949
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0031624 - ubiquitin conjugating enzyme binding
GO:0031647 - regulation of protein stability
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
and 1 others

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Homologous interactions 0

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Last updated: 15 Jul 2024