HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: ATAD1 (Q8NBU5)
Outer mitochondrial transmembrane helix translocase (EC 7.4.2.-) (ATPase family AAA domain-containing protein 1) (hATAD1) (Thorase)
Gene: ATAD1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29180628
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	AAA~ubiquitin
Common GO terms	GO:0005741 - mitochondrial outer membrane GO:0005829 - cytosol GO:0007612 - learning
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 465 Hs			1 361
+	Hs
		226057 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		KTNA1_HUMAN (3-358): 2.78e-107: 324: 31.00
+	Hs
		227077 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PRS10_HUMAN (8-358): 1.14e-103: 312: 28.65
+	Hs
		227061 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PRS8_HUMAN (13-359): 2.25e-102: 309: 28.00
+	Hs
		226773 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PRS6B_HUMAN (8-338): 5.06e-99: 301: 26.65
+	Hs
		226980 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		TERA_HUMAN (77-356): 3.22e-89: 286: 33.33
+	Hs
		226044 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		VPS4B_HUMAN (87-318): 1.56e-50: 176: 44.02
+	Hs
		265448 ARI1_HUMAN (163-464): 3.95e-74: 244: 19.67		KTNA1_HUMAN (3-358): 2.78e-107: 324: 31.00
+	Hs
		875476 ARI1_HUMAN (163-464): 3.95e-74: 244: 19.67		TERA_HUMAN (77-356): 3.22e-89: 286: 33.33
+	Hs
		312526 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		TERA_HUMAN (77-356): 3.22e-89: 286: 33.33
+	Hs
		474950 UBB_HUMAN (1-234): 1.14e-59: 197: 17.92		PRS6B_HUMAN (8-338): 5.06e-99: 301: 26.65
+	Sc
		477159 UBI4P_YEAST (1-229): 3.48e-61: 205: 18.72		CDC48_YEAST (12-359): 4.87e-90: 289: 25.20
+	Hs
		474971 UBB_HUMAN (1-234): 1.14e-59: 197: 17.92		TERA_HUMAN (77-356): 3.22e-89: 286: 33.33
+	Hs
		475580 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		PRS10_HUMAN (8-358): 1.14e-103: 312: 28.65
+	Hs
		475570 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		PRS8_HUMAN (13-359): 2.25e-102: 309: 28.00
+	Hs
		475459 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		PRS6B_HUMAN (8-338): 5.06e-99: 301: 26.65
+	Hs
		875357 RN19A_HUMAN (236-452): 6.6e-31: 128: 21.62		TERA_HUMAN (77-356): 3.22e-89: 286: 33.33
+	Mm
		841457 RN19A_MOUSE (236-452): 2.59e-30: 126: 21.62		TERA_MOUSE (77-356): 3.22e-89: 286: 33.33
+	Hs
		475529 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		TERA_HUMAN (77-356): 3.22e-89: 286: 33.33
+	Hs
		87546 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		C9JUP7_HUMAN (2-360): 1.43e-89: 286: 28.19
+	Hs
		476034 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		KATL2_HUMAN (85-357): 1.16e-47: 171: 37.59