HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: RBM12 (Q9NTZ6)
RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN)
Gene: RBM12

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.50	0.585

Property	Details
Experiments	35509820, 35987950, 35256949
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 465 Hs			1 932
+	Hs
		226932 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		HNRPF_HUMAN (537-931): 1.62e-28: 121: 16.92
+	Hs
		226642 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		HNRH1_HUMAN (537-931): 1.63e-25: 112: 16.58
+	Hs
		226990 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		HNRH2_HUMAN (537-648): 2.34e-21: 100: 13.56
+	Hs
		227486 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		SART3_HUMAN (369-670): 5.46e-16: 85.2: 18.73
+	Hs
		226641 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		HNRH3_HUMAN (545-621): 2.99e-14: 77.1: 22.08
+	Hs
		226485 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		NUCL_HUMAN (414-616): 3.4e-13: 75.5: 16.10
+	Hs
		227299 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		GRSF1_HUMAN (290-379): 4.48e-13: 74.5: 21.11
+	Hs
		227354 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PABP4_HUMAN (844-929): 1.59e-10: 67: 20.93
+	Hs
		227642 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PAP1L_HUMAN (844-929): 7.58e-10: 64.7: 19.77
+	Hs
		226375 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PABP1_HUMAN (844-929): 9.23e-10: 64.3: 20.93
+	Hs
		227999 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		RB12B_HUMAN (544-686): 5.9e-09: 62.2: 16.08
+	Hs
		228678 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PABP3_HUMAN (806-929): 4.77e-09: 62: 18.55
+	Hs
		1031383 CUL9_HUMAN (30-463): 1.19e-80: 274: 18.58		PABP4_HUMAN (844-929): 1.59e-10: 67: 20.93
+	Hs
		312525 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		HNRPF_HUMAN (537-931): 1.62e-28: 121: 16.92
+	Hs
		312494 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		HNRH1_HUMAN (537-931): 1.63e-25: 112: 16.58
+	Hs
		312607 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		SART3_HUMAN (369-670): 5.46e-16: 85.2: 18.73
+	Sc
		477234 UBI4P_YEAST (1-229): 3.48e-61: 205: 18.72		NOP4_YEAST (302-595): 2.63e-18: 92.1: 15.41
+	Hs
		312474 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		NUCL_HUMAN (414-616): 3.4e-13: 75.5: 16.10
+	Hs
		312462 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		PABP1_HUMAN (844-929): 9.23e-10: 64.3: 20.93
+	Hs
		475288 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		PABP1_HUMAN (844-929): 9.23e-10: 64.3: 20.93