HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: PA2G4 (Q9UQ80)
Proliferation-associated protein 2G4 (Cell cycle protein p38-2G4 homolog) (hG4-1) (ErbB3-binding protein 1)
Gene: PA2G4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	25959826, 35509820, 35256949
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003714 - transcription corepressor activity GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 394
+	Hs
		226886 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		MAP2_HUMAN (2-336): 2.64e-110: 333: 22.71
+	Hs
		226946 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		MAP11_HUMAN (1-269): 1.11e-92: 285: 14.03
+	Hs
		226388 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PEPD_HUMAN (3-271): 8.37e-59: 200: 11.80
+	Hs
		228793 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		XPP3_HUMAN (7-272): 5.21e-58: 198: 12.41
+	Zm
		24710 A0A1D6IJX7_MAIZE (233-459): 1.19e-26: 116: 21.70		B4FQH9_MAIZE (10-272): 2.54e-59: 202: 11.04