Interactor 1: SMCA5 (O60264)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin A5) (EC 3.6.4.-) (Sucrose nonfermenting protein 2 homolog) (hSNF2H)
Gene: SMARCA5

Interactor 2: DPOE3 (Q9NRF9)
DNA polymerase epsilon subunit 3 (Arsenic-transactivated protein) (AsTP) (Chromatin accessibility complex 17 kDa protein) (CHRAC-17) (HuCHRAC17) (DNA polymerase II subunit 3) (DNA polymerase epsilon subunit p17)
Gene: POLE3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 0.60 0.721

The method score is based on:

Property Details
Experiments 10880450, 35271311, 33961781, 12434153, 14759371
Identification Methods biochemical, affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type association, physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005721 - pericentric heterochromatin
GO:0006275 - regulation of DNA replication
GO:0006334 - nucleosome assembly
and 4 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 1052
Hs

1 147
+ Hs
+ Dm
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024