HitPredict

Interactor 1: KDM1A (O60341)
Lysine-specific histone demethylase 1A (EC 1.14.99.66) (BRAF35-HDAC complex protein BHC110) (Flavin-containing amine oxidase domain-containing protein 2) ([histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1A)
Gene: KDM1A

Interactor 2: H33 (P84243)
Histone H3.3
Gene: H3-3A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36089195
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Amino_oxidase~Histone
Common GO terms	GO:0000781 - chromosome, telomeric region GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0032991 - protein-containing complex
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 852 Hs			1 136
+	Hs
		232094 KDM1A_HUMAN (1-852): 0: 936: 100.00		H31_HUMAN (1-136): 3.08e-60: 183: 96.32
+	Hs
		232190 KDM1A_HUMAN (1-852): 0: 936: 100.00		H31T_HUMAN (1-136): 2.58e-59: 181: 93.38
+	Hs
		232270 KDM1A_HUMAN (1-852): 0: 936: 100.00		H32_HUMAN (1-136): 5.32e-59: 180: 97.06
+	Hs
		232248 KDM1A_HUMAN (1-852): 0: 936: 100.00		H3C_HUMAN (1-136): 1.99e-56: 173: 95.59
+	Dm
		356119 LSDA_DROME (35-844): 0: 747: 50.41		H3_DROME (1-136): 5.32e-59: 180: 97.06
+	Hs
		934992 KDM1B_HUMAN (160-501): 1.3e-62: 228: 24.86		H31_HUMAN (1-136): 3.08e-60: 183: 96.32
+	Hs
		952473 KDM1B_HUMAN (160-501): 1.3e-62: 228: 24.86		H33_HUMAN (1-136): 1.12e-59: 182: 100.00
+	Hs
		1086222 KDM1B_HUMAN (160-501): 1.3e-62: 228: 24.86		H31T_HUMAN (1-136): 2.58e-59: 181: 93.38
+	Hs
		935012 SMRC2_HUMAN (5-300): 1.17e-57: 216: 15.14		H31_HUMAN (1-136): 3.08e-60: 183: 96.32
+	Hs
		935075 SMRC1_HUMAN (34-300): 1.41e-57: 216: 16.96		H31_HUMAN (1-136): 3.08e-60: 183: 96.32
+	Hs
		952485 SMRC2_HUMAN (5-300): 1.17e-57: 216: 15.14		H33_HUMAN (1-136): 1.12e-59: 182: 100.00
+	Hs
		952518 SMRC1_HUMAN (34-300): 1.41e-57: 216: 16.96		H33_HUMAN (1-136): 1.12e-59: 182: 100.00
+	Hs
		828334 SMRC1_HUMAN (34-300): 1.41e-57: 216: 16.96		CENPA_HUMAN (9-133): 2.42e-45: 146: 50.76