HitPredict

Interactor 1: TBCD4 (O60343)
TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160)
Gene: TBC1D4

Interactor 2: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.91	0.60	0.742

Property	Details
Experiments	25770209, 25266655, 33961781, 35271311, 36931259, 15161933, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0031982 - vesicle
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1298 Hs			1 245
+	Hs
		232659 TBCD4_HUMAN (1-1298): 0: 1532: 100.00		1433E_HUMAN (2-241): 9.9e-144: 403: 68.18
+	Hs
		232640 TBCD4_HUMAN (1-1298): 0: 1532: 100.00		1433T_HUMAN (1-245): 2.6e-140: 395: 79.59
+	Hs
		232646 TBCD4_HUMAN (1-1298): 0: 1532: 100.00		1433B_HUMAN (1-242): 9.01e-140: 393: 87.60
+	Mm
		910295 TBCD4_MOUSE (1-1298): 0: 1473: 89.53		1433E_MOUSE (2-241): 9.9e-144: 403: 68.18
+	Hs
		232657 TBCD4_HUMAN (1-1298): 0: 1532: 100.00		1433G_HUMAN (1-240): 2.37e-108: 314: 74.59
+	Hs
		232667 TBCD4_HUMAN (1-1298): 0: 1532: 100.00		1433F_HUMAN (2-240): 1.26e-107: 312: 74.49
+	Mm
		1207476 TBCD4_MOUSE (1-1298): 0: 1473: 89.53		1433B_MOUSE (1-242): 3.77e-128: 364: 87.19
+	Hs
		232647 TBCD4_HUMAN (1-1298): 0: 1532: 100.00		1433S_HUMAN (1-237): 8.27e-104: 302: 71.97
+	Hs
		927234 TBCD1_HUMAN (36-1279): 0: 1168: 48.09		1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00
+	Hs
		909751 TBCD1_HUMAN (36-1279): 0: 1168: 48.09		1433E_HUMAN (2-241): 9.9e-144: 403: 68.18
+	Hs
		647059 TBCD1_HUMAN (36-1279): 0: 1168: 48.09		1433T_HUMAN (1-245): 2.6e-140: 395: 79.59
+	Hs
		683502 TBCD1_HUMAN (36-1279): 0: 1168: 48.09		1433B_HUMAN (1-242): 9.01e-140: 393: 87.60
+	Hs
		904793 TBCD1_HUMAN (36-1279): 0: 1168: 48.09		1433G_HUMAN (1-240): 2.37e-108: 314: 74.59
+	Hs
		982218 TBCD1_HUMAN (36-1279): 0: 1168: 48.09		1433F_HUMAN (2-240): 1.26e-107: 312: 74.49
+	Hs
		904782 Q7Z6H2_HUMAN (344-1279): 0: 826: 52.59		1433G_HUMAN (1-240): 2.37e-108: 314: 74.59
+	Hs
		683395 TB10B_HUMAN (579-1213): 2.51e-101: 343: 17.48		1433B_HUMAN (1-242): 9.01e-140: 393: 87.60
+	Hs
		683573 TB22A_HUMAN (678-1176): 4e-88: 298: 13.94		1433B_HUMAN (1-242): 9.01e-140: 393: 87.60
+	Hs
		904748 TBCD9_HUMAN (641-1277): 3.99e-102: 355: 17.81		1433G_HUMAN (1-240): 2.37e-108: 314: 74.59
+	Hs
		904643 TB10B_HUMAN (579-1213): 2.51e-101: 343: 17.48		1433G_HUMAN (1-240): 2.37e-108: 314: 74.59
+	Hs
		982075 TB10B_HUMAN (579-1213): 2.51e-101: 343: 17.48		1433F_HUMAN (2-240): 1.26e-107: 312: 74.49