Interactor 1: PBX1 (P40424)
Pre-B-cell leukemia transcription factor 1 (Homeobox protein PBX1) (Homeobox protein PRL)
Gene: PBX1

Interactor 2: PKNX2 (Q96KN3)
Homeobox protein PKNOX2 (Homeobox protein PREP-2) (PBX/knotted homeobox 2)
Gene: PKNOX2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.61 1.00 0.783

The method score is based on:

Property Details
Experiments 33961781, 20211142
Identification Methods affinity chromatography technology, two hybrid array, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Homeobox_KN~Homeobox_KN
Common GO terms GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0006357 - regulation of transcription by RNA polymerase II
and 1 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 430
Hs

1 472
+ Mm
+ Hs
+ Mm
+ Mm
+ Mm
+ Hs
+ Hs
+ Mm
+ Mm
+ Mm
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs
+ Mm
+ Mm
+ Mm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024