HitPredict

Interactor 1: PHLP1 (O60346)
PH domain leucine-rich repeat-containing protein phosphatase 1 (EC 3.1.3.16) (Pleckstrin homology domain-containing family E member 1) (PH domain-containing family E member 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP)
Gene: PHLPP1

Interactor 2: RU2A (P09661)
U2 small nuclear ribonucleoprotein A' (U2 snRNP A')
Gene: SNRPA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33397691
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1717 Hs			1 255
+	Hs
		232877 PHLP1_HUMAN (1-1717): 0: 1504: 100.00		SCRIB_HUMAN (9-248): 4.3e-28: 114: 15.70
+	Hs
		1172960 PHLP2_HUMAN (469-1717): 0: 884: 53.15		DAA11_HUMAN (1-247): 3.37e-46: 162: 21.34
+	At
		1325020 PXL1_ARATH (790-1351): 2.64e-76: 278: 14.66		PXL1_ARATH (1-82): 3.91e-12: 67.6: 13.79
+	Zm
		19443 A0A1D6HD42_MAIZE (368-964): 1.94e-67: 251: 15.19		A0A1D6HD42_MAIZE (67-224): 1.69e-12: 68.8: 14.37
+	Hs
		453839 LRRK2_HUMAN (716-1019): 5.96e-18: 93.2: 29.32		RU2A_HUMAN (1-255): 9.82e-54: 175: 100.00
+	Hs
		1050066 LRC40_HUMAN (691-1141): 7.56e-25: 113: 25.00		SCRIB_HUMAN (9-248): 4.3e-28: 114: 15.70
+	Hs
		1130680 LRRK2_HUMAN (716-1019): 5.96e-18: 93.2: 29.32		CEP72_HUMAN (4-213): 2.44e-34: 132: 20.36
+	At
		1114706 ERECT_ARATH (1013-1344): 1.87e-33: 142: 17.23		PXL1_ARATH (1-82): 3.91e-12: 67.6: 13.79
+	Hs
		2885 LRRK2_HUMAN (716-1019): 5.96e-18: 93.2: 29.32		A0A0G2JPP5_HUMAN (9-248): 2.89e-28: 114: 15.70
+	Hs
		1023176 LRRK2_HUMAN (716-1019): 5.96e-18: 93.2: 29.32		FLII_HUMAN (18-248): 1.63e-25: 106: 13.13
+	Hs
		1105460 LRRK2_HUMAN (716-1019): 5.96e-18: 93.2: 29.32		LRRK1_HUMAN (43-233): 9.81e-22: 96.1: 14.93
+	Hs
		1120217 LRC40_HUMAN (691-1141): 7.56e-25: 113: 25.00		LRC23_HUMAN (24-146): 2.51e-13: 70.5: 29.27
+	Dm
		1181694 SCRIB_DROME (739-1116): 5.3e-16: 86.7: 28.29		SCRIB_DROME (31-248): 4.2e-20: 91.1: 12.97
+	Hs
		1050046 LRRC1_HUMAN (896-1143): 8.91e-09: 62: 28.74		SCRIB_HUMAN (9-248): 4.3e-28: 114: 15.70
+	Hs
		1130525 LRRK2_HUMAN (716-1019): 5.96e-18: 93.2: 29.32		AN32E_HUMAN (3-146): 1.11e-11: 65.1: 28.28
+	Hs
		1078940 LRRK2_HUMAN (716-1019): 5.96e-18: 93.2: 29.32		TBCE_HUMAN (16-235): 6.1e-10: 60.7: 15.95
+	Hs
		3599 LRRK2_HUMAN (716-1019): 5.96e-18: 93.2: 29.32		A0A140VK83_HUMAN (24-151): 9.53e-09: 57: 28.91