HitPredict

Interactor 1: PHLP1 (O60346)
PH domain leucine-rich repeat-containing protein phosphatase 1 (EC 3.1.3.16) (Pleckstrin homology domain-containing family E member 1) (PH domain-containing family E member 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP)
Gene: PHLPP1

Interactor 2: RAPH1 (Q70E73)
Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 18 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 9 protein) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1)
Gene: RAPH1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	33397691
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~PH, PH~RA
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0007165 - signal transduction
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 1717 Hs			1 1250
+	Hs
		232742 PHLP1_HUMAN (1-1717): 0: 1504: 100.00		ANR17_HUMAN (543-1095): 3.34e-14: 80.2: 12.82
+	Hs
		257621 LRRK2_HUMAN (716-1019): 5.96e-18: 93.2: 29.32		ANR17_HUMAN (543-1095): 3.34e-14: 80.2: 12.82
+	Hs
		92119 LRRK2_HUMAN (716-1019): 5.96e-18: 93.2: 29.32		NACAM_HUMAN (514-1248): 1.61e-12: 74.8: 13.67