Interactor 1: FZD6 (O60353)
Frizzled-6 (Fz-6) (hFz6)
Gene: FZD6

Interactor 2: SFRP1 (Q8N474)
Secreted frizzled-related protein 1 (FRP-1) (sFRP-1) (Secreted apoptosis-related protein 2) (SARP-2)
Gene: SFRP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.44 1.00 0.665

The method score is based on:

Property Details
Experiments 10347172
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Frizzled~Fz, Fz~Fz
Common GO terms GO:0005886 - plasma membrane
GO:0009986 - cell surface
GO:0017147 - Wnt-protein binding
GO:0035567 - non-canonical Wnt signaling pathway
GO:0060070 - canonical Wnt signaling pathway
and 1 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 706
Hs

1 314
+ Hs
+ Rn
+ Rn
+ Rn
+ Hs
+ Hs
+ Hs
+ Dm
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024