HitPredict

Interactor 1: HBP1 (O60381)
HMG box-containing protein 1 (HMG box transcription factor 1) (High mobility group box transcription factor 1)
Gene: HBP1

Interactor 2: RB (P06400)
Retinoblastoma-associated protein (p105-Rb) (p110-RB1) (pRb) (Rb) (pp110)
Gene: RB1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.631

Property	Details
Experiments	9178770, 23859194
Identification Methods	two hybrid, pull down, affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0051726 - regulation of cell cycle
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 514 Hs			1 928
+	Hs
		414358 CIC_HUMAN (407-512): 6.93e-40: 156: 33.62		RB_HUMAN (1-928): 0: 1323: 100.00
+	Hs
		414394 LEF1_HUMAN (364-508): 1.1e-30: 125: 23.45		RB_HUMAN (1-928): 0: 1323: 100.00
+	Hs
		233832 HBP1_HUMAN (1-514): 0: 889: 100.00		RBL2_HUMAN (638-875): 1.32e-58: 220: 26.87