Protein: PNKD
Probable hydrolase PNKD (EC 3.-.-.-) (Myofibrillogenesis regulator 1) (MR-1) (Paroxysmal nonkinesiogenic dyskinesia protein) (Trans-activated by hepatitis C virus core protein 2)

Gene: PNKD
Organism: Homo sapiens
Interactions: 136
UniProt ID: Q8N490

Gene Ontology (top 5):
GO:0004416 - hydroxyacylglutathione hydrolase activity
GO:0005634 - nucleus
GO:0005739 - mitochondrion
GO:0016020 - membrane
GO:0019243 - methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

796308

MAGAB
Melanoma-associated antigen 11

4

1

High-throughput

0.700

High

1233317

PBIP1
Pre-B-cell leukemia transcription factor-interacting protein 1

3

5

High-throughput

0.667

High

819101

LSS
Lanosterol synthase

3

0

High-throughput

0.638

High

236439

RNBP6
Ran-binding protein 6

2

2

High-throughput

0.611

High

312328

IPO7
Importin-7

2

5

High-throughput

0.611

High

1063341

CND1
Condensin complex subunit 1

2

1

High-throughput

0.611

High

1066393

KIF14
Kinesin-like protein KIF14

2

1

High-throughput

0.611

High

1232542

STAG2
Cohesin subunit SA-2

2

1

High-throughput

0.611

High

1233311

STAG1
Cohesin subunit SA-1

2

1

High-throughput

0.611

High

1233325

IPO9
Importin-9

2

5

High-throughput

0.611

High

1233334

GOLP3
Golgi phosphoprotein 3

2

2

High-throughput

0.611

High

1233350

PP6R1
Serine/threonine-protein phosphatase 6 regulatory subunit 1

2

1

High-throughput

0.611

High

1233352

DICER
Endoribonuclease Dicer

2

1

High-throughput

0.611

High

395178

A4
Amyloid-beta precursor protein

2

2

High-throughput

0.602

High

157750

GEMI2
Gem-associated protein 2

2

0

High-throughput

0.585

High

267177

GEMI
Geminin

2

0

High-throughput

0.585

High

327682

ECD
Protein ecdysoneless homolog

2

0

High-throughput

0.585

High

777222

PEX19
Peroxisomal biogenesis factor 19

2

0

High-throughput

0.585

High

835081

TSC2
Tuberin

2

0

High-throughput

0.585

High

880025

RRP1
Ribosomal RNA processing protein 1 homolog A

2

0

High-throughput

0.585

High

1037482

ASAH1
Acid ceramidase

2

0

High-throughput

0.585

High

1047946

KCC1A
Calcium/calmodulin-dependent protein kinase type 1

2

0

High-throughput

0.585

High

1075608

TRBP2
RISC-loading complex subunit TARBP2

2

0

High-throughput

0.585

High

1082060

TAF12
Transcription initiation factor TFIID subunit 12

2

0

High-throughput

0.585

High

1110492

GON4L
GON-4-like protein

2

0

High-throughput

0.585

High

1148309

INT3
Integrator complex subunit 3

2

0

High-throughput

0.585

High

1186176

DYM
Dymeclin

2

0

High-throughput

0.585

High

1188031

SETX
Probable helicase senataxin

2

0

High-throughput

0.585

High

1205762

PRGC2
Peroxisome proliferator-activated receptor gamma coactivator 1-beta

2

0

High-throughput

0.585

High

1232459

VPS8
Vacuolar protein sorting-associated protein 8 homolog

2

0

High-throughput

0.585

High

1233304

MIGA1
Mitoguardin 1

2

0

High-throughput

0.585

High

1233312

ATRIP
ATR-interacting protein

2

0

High-throughput

0.585

High

1233313

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

2

0

High-throughput

0.585

High

1233319

KBP
KIF-binding protein

2

0

High-throughput

0.585

High

1233321

SAAL1
Protein SAAL1

2

0

High-throughput

0.585

High

1233327

DCNL5
DCN1-like protein 5

2

0

High-throughput

0.585

High

1233329

NUP85
Nuclear pore complex protein Nup85

2

0

High-throughput

0.585

High

1233332

XPO4
Exportin-4

2

0

High-throughput

0.585

High

1233339

MLXIP
MLX-interacting protein

2

0

High-throughput

0.585

High

1233341

SOSSC
SOSS complex subunit C

2

0

High-throughput

0.585

High

1233342

DIAP3
Protein diaphanous homolog 3

2

0

High-throughput

0.585

High

1233346

ARMX3
Armadillo repeat-containing X-linked protein 3

2

0

High-throughput

0.585

High

1233351

EXOC7
Exocyst complex component 7

2

0

High-throughput

0.585

High

155604

TNPO2
Transportin-2

2

4

High-throughput

0.584

High

647627

MK03
Mitogen-activated protein kinase 3

2

0

Small-scale

0.576

High

369993

ESR1
Estrogen receptor

2

2

High-throughput

0.571

High

178218

IPO8
Importin-8

2

5

High-throughput

0.558

High

1136944

BIG3
Brefeldin A-inhibited guanine nucleotide-exchange protein 3

2

1

High-throughput

0.558

High

1202988

LIPB1
Liprin-beta-1

2

4

High-throughput

0.558

High

1233309

CIP2A
Protein CIP2A

2

4

High-throughput

0.558

High

1233318

HOOK2
Protein Hook homolog 2

2

4

High-throughput

0.558

High

1233333

GLP3L
Golgi phosphoprotein 3-like

2

2

High-throughput

0.558

High

1233347

EI2BD
Translation initiation factor eIF2B subunit delta

2

1

High-throughput

0.558

High

1233348

IPO11
Importin-11

2

5

High-throughput

0.558

High

725979

ADDA
Alpha-adducin

1

1

High-throughput

0.536

High

1119179

GREB1
Protein GREB1

1

1

High-throughput

0.536

High

1233331

GRB1L
GREB1-like protein

1

1

High-throughput

0.536

High

789880

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

0

High-throughput

0.513

High

902962

DCAF7
DDB1- and CUL4-associated factor 7

1

0

High-throughput

0.513

High

905478

TIM10
Mitochondrial import inner membrane translocase subunit Tim10

1

0

High-throughput

0.513

High

1033507

ILK
Integrin-linked protein kinase

1

0

High-throughput

0.513

High

1046513

TBB2A
Tubulin beta-2A chain

1

0

High-throughput

0.513

High

1048353

SCRB2
Lysosome membrane protein 2

1

0

High-throughput

0.513

High

1121239

KLH22
Kelch-like protein 22

1

0

High-throughput

0.513

High

1170434

UBR3
E3 ubiquitin-protein ligase UBR3

1

0

High-throughput

0.513

High

1233314

NICA
Nicastrin

1

0

High-throughput

0.513

High

1233349

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

0

High-throughput

0.513

High

1233355

T10B
Mitochondrial import inner membrane translocase subunit Tim10 B

1

0

High-throughput

0.513

High

476045

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

2

High-throughput

0.501

High

507629

ACADM
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial

1

0

High-throughput

0.493

High

614381

PPIB
Peptidyl-prolyl cis-trans isomerase B

1

0

High-throughput

0.493

High

157961

KLF11
Krueppel-like factor 11

1

0

High-throughput

0.493

High

69735

ESPN
Espin

1

1

High-throughput

0.489

High

726045

ADDB
Beta-adducin

1

1

High-throughput

0.489

High

1073359

NR6A1
Nuclear receptor subfamily 6 group A member 1

1

2

High-throughput

0.489

High

1233315

TBCD5
TBC1 domain family member 5

1

1

High-throughput

0.489

High

257198

PP6R2
Serine/threonine-protein phosphatase 6 regulatory subunit 2

1

1

High-throughput

0.479

High

646223

STOM
Stomatin

1

1

High-throughput

0.479

High

718985

PHB1
Prohibitin 1

1

1

High-throughput

0.479

High

789310

CNDD3
Condensin-2 complex subunit D3

1

1

High-throughput

0.479

High

969849

KIF23
Kinesin-like protein KIF23

1

1

High-throughput

0.479

High

1025654

EI2BE
Translation initiation factor eIF2B subunit epsilon

1

2

High-throughput

0.479

High

1085436

MK06
Mitogen-activated protein kinase 6

1

1

High-throughput

0.479

High

1233316

ESR2
Estrogen receptor beta

1

2

High-throughput

0.479

High

1233338

SFXN1
Sideroflexin-1

1

1

High-throughput

0.479

High

1233345

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

103664

G5E962
MAGE family member A11

1

1

High-throughput

0.470

High

1233328

NUP58
Nucleoporin p58/p45

1

1

High-throughput

0.470

High

118577

EYA2
Eyes absent homolog 2

1

0

High-throughput

0.458

High

167972

NPC1
NPC intracellular cholesterol transporter 1

1

0

High-throughput

0.458

High

740936

FDFT
Squalene synthase

1

0

High-throughput

0.458

High

779735

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

884757

NU107
Nuclear pore complex protein Nup107

1

0

High-throughput

0.458

High

1152356

CNDH2
Condensin-2 complex subunit H2

1

0

High-throughput

0.458

High

1233305

NUP37
Nucleoporin Nup37

1

0

High-throughput

0.458

High

1233306

PJA1
E3 ubiquitin-protein ligase Praja-1

1

0

High-throughput

0.458

High

1233330

RTF2
Replication termination factor 2

1

0

High-throughput

0.458

High

1233337

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

883561

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

1

High-throughput

0.445

High

1117735

Q4LE60
TNPO2 variant protein

1

4

High-throughput

0.445

High

416471

S10A9
Protein S100-A9

1

0

Small-scale

0.438

High

834430

EI2BB
Translation initiation factor eIF2B subunit beta

1

1

High-throughput

0.437

High

1233320

RNF31
E3 ubiquitin-protein ligase RNF31

1

4

High-throughput

0.437

High

1233335

Q9H4D1
Protein kinase

1

1

High-throughput

0.437

High

1233336

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.437

High

1233340

EI2BG
Translation initiation factor eIF2B subunit gamma

1

1

High-throughput

0.437

High

1233353

COA3
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial

1

0

Small-scale

0.426

High

1159146

ANM9
Protein arginine N-methyltransferase 9

3

0

High-throughput

0.347

High

130083

EXOC5
Exocyst complex component 5

2

0

High-throughput

0.318

High

171152

CETN3
Centrin-3

2

0

High-throughput

0.318

High

203388

IF4G3
Eukaryotic translation initiation factor 4 gamma 3

2

0

High-throughput

0.318

High

276038

EIF3J
Eukaryotic translation initiation factor 3 subunit J

2

0

High-throughput

0.318

High

858010

NUP98
Nuclear pore complex protein Nup98-Nup96

2

0

High-throughput

0.318

High

1014049

AP1B1
AP-1 complex subunit beta-1

2

0

High-throughput

0.318

High

1129240

P4R3B
Serine/threonine-protein phosphatase 4 regulatory subunit 3B

2

0

High-throughput

0.318

High

1190546

HEAT3
HEAT repeat-containing protein 3

2

0

High-throughput

0.318

High

1233303

AL14E
ARL14 effector protein

2

0

High-throughput

0.318

High

1233307

FBX30
F-box only protein 30

2

0

High-throughput

0.318

High

1233308

TBC15
TBC1 domain family member 15

2

0

High-throughput

0.318

High

1233310

DCA11
DDB1- and CUL4-associated factor 11

2

0

High-throughput

0.318

High

1233323

RADIL
Ras-associating and dilute domain-containing protein

2

0

High-throughput

0.318

High

1233326

HAUS7
HAUS augmin-like complex subunit 7

2

0

High-throughput

0.318

High

1233344

TFP11
Tuftelin-interacting protein 11

2

0

High-throughput

0.318

High

1233354

AR2BP
ADP-ribosylation factor-like protein 2-binding protein

2

0

High-throughput

0.318

High

1183860

KCTD9
BTB/POZ domain-containing protein KCTD9

1

0

High-throughput

0.299

High

299272

FARP2
FERM, ARHGEF and pleckstrin domain-containing protein 2

2

0

High-throughput

0.298

High

1233322

OTUB1
Ubiquitin thioesterase OTUB1

2

0

High-throughput

0.298

High

245373

RAMP3
Receptor activity-modifying protein 3

1

0

High-throughput

0.279

Low

819066

AL3B2
Aldehyde dehydrogenase family 3 member B2

1

0

High-throughput

0.279

Low

1139925

FHI2A
FHF complex subunit HOOK interacting protein 2A

1

0

High-throughput

0.279

Low

1157066

ARMC6
Armadillo repeat-containing protein 6

1

0

High-throughput

0.279

Low

1026188

PAK1
Serine/threonine-protein kinase PAK 1

1

0

High-throughput

0.268

Low

163624

BTAF1
TATA-binding protein-associated factor 172

1

0

High-throughput

0.249

Low

1015913

NU160
Nuclear pore complex protein Nup160

1

0

High-throughput

0.249

Low

1233343

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

0

High-throughput

0.249

Low

1233324

NEUL4
Neuralized-like protein 4

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024