HitPredict

Interactor 1: PEPL (O60437)
Periplakin (190 kDa paraneoplastic pemphigus antigen) (195 kDa cornified envelope precursor protein)
Gene: PPL

Interactor 2: KI3S1 (Q14943)
Killer cell immunoglobulin-like receptor 3DS1 (Natural killer-associated transcript 10) (NKAT-10)
Gene: KIR3DS1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1756 Hs			1 382
+	Hs
		551706 DESP_HUMAN (1031-1718): 1.69e-13: 78.7: 12.03		KI3S1_HUMAN (1-382): 3.98e-106: 319: 100.00
+	Hs
		508011 PLEC_HUMAN (1-1360): 9.93e-42: 171: 10.15		FGFR1_HUMAN (3-369): 3.89e-60: 209: 14.18
+	Hs
		508036 GRDN_HUMAN (1065-1598): 6.32e-11: 70.1: 23.13		FGFR1_HUMAN (3-369): 3.89e-60: 209: 14.18
+	Hs
		601523 GRDN_HUMAN (1065-1598): 6.32e-11: 70.1: 23.13		FGFR2_HUMAN (2-379): 8.05e-60: 208: 13.78
+	Hs
		601499 DYST_HUMAN (724-1629): 8.16e-09: 63.1: 11.55		FGFR2_HUMAN (2-379): 8.05e-60: 208: 13.78
+	Hs
		724846 MYH9_HUMAN (772-1656): 1.06e-32: 141: 16.74		MYLK_HUMAN (218-312): 1.49e-10: 65.2: 8.08