HitPredict

Interactor 1: VINEX (O60504)
Vinexin (SH3-containing adapter molecule 1) (SCAM-1) (Sorbin and SH3 domain-containing protein 3)
Gene: SORBS3

Interactor 2: ACTS (P68133)
Actin, alpha skeletal muscle (EC 3.6.4.-) (Alpha-actin-1) [Cleaved into: Actin, alpha skeletal muscle, intermediate form]
Gene: ACTA1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005200 - structural constituent of cytoskeleton GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 671 Hs			1 377
+	Hs
		596202 NEBU_HUMAN (12-671): 4.58e-53: 200: 12.62		ACTB_HUMAN (5-377): 0: 604: 93.83
+	Hs
		596210 NEBU_HUMAN (12-671): 4.58e-53: 200: 12.62		ACTH_HUMAN (4-377): 0: 597: 98.40
+	Hs
		891762 SRC8_HUMAN (482-669): 6.12e-21: 98.9: 14.89		ACTB_HUMAN (5-377): 0: 604: 93.83
+	Hs
		929863 SRC8_HUMAN (482-669): 6.12e-21: 98.9: 14.89		ACTG_HUMAN (4-377): 0: 604: 93.85
+	Hs
		932154 SRC8_HUMAN (482-669): 6.12e-21: 98.9: 14.89		ACTC_HUMAN (1-377): 0: 604: 98.94
+	Hs
		892005 SRBS1_HUMAN (522-671): 2.49e-20: 98.4: 35.53		ACTB_HUMAN (5-377): 0: 604: 93.83
+	Hs
		932362 SRBS1_HUMAN (522-671): 2.49e-20: 98.4: 35.53		ACTC_HUMAN (1-377): 0: 604: 98.94
+	Hs
		930053 PACN2_HUMAN (433-671): 4.38e-18: 89.7: 15.98		ACTG_HUMAN (4-377): 0: 604: 93.85
+	Hs
		932316 SH3K1_HUMAN (614-671): 3.44e-13: 74.9: 25.86		ACTC_HUMAN (1-377): 0: 604: 98.94
+	Hs
		932975 SPTN1_HUMAN (511-671): 1.08e-12: 73.9: 9.94		ACTS_HUMAN (1-377): 0: 605: 100.00
+	Hs
		891755 SPTN1_HUMAN (511-671): 1.08e-12: 73.9: 9.94		ACTB_HUMAN (5-377): 0: 604: 93.83
+	Hs
		891821 SH319_HUMAN (39-671): 7.07e-13: 73.9: 10.88		ACTB_HUMAN (5-377): 0: 604: 93.83
+	Hs
		929856 SPTN1_HUMAN (511-671): 1.08e-12: 73.9: 9.94		ACTG_HUMAN (4-377): 0: 604: 93.85
+	Hs
		932145 SPTN1_HUMAN (511-671): 1.08e-12: 73.9: 9.94		ACTC_HUMAN (1-377): 0: 604: 98.94
+	Hs
		892142 CD2AP_HUMAN (614-671): 8.75e-11: 67.2: 27.12		ACTB_HUMAN (5-377): 0: 604: 93.83
+	Hs
		932478 CD2AP_HUMAN (614-671): 8.75e-11: 67.2: 27.12		ACTC_HUMAN (1-377): 0: 604: 98.94