Protein: FPK1
Flippase kinase 1 (EC 2.7.11.1)

Gene: FPK1
Organism: Saccharomyces cerevisiae S288C
Interactions: 61
UniProt ID: P53739

Gene Ontology (top 5):
GO:0000749 - response to pheromone triggering conjugation with cellular fusion
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

554720

YPK1
Serine/threonine-protein kinase YPK1

4

16

Small-scale

0.899

High

364672

CDK1
Cyclin-dependent kinase 1

2

9

High-throughput

0.812

High

645960

DBF2
Cell cycle protein kinase DBF2

2

18

Small-scale

0.778

High

793185

AKL1
Serine/threonine-protein kinase AKL1

2

12

Small-scale

0.778

High

672198

KIN82
Serine/threonine-protein kinase KIN82

1

17

High-throughput

0.665

High

602582

PHO85
Cyclin-dependent protein kinase PHO85

1

10

Small-scale

0.647

High

642436

MCK1
Protein kinase MCK1

1

20

High-throughput

0.647

High

656825

KC12
Casein kinase I homolog 2

1

7

High-throughput

0.647

High

667041

PCL1
PHO85 cyclin-1

1

1

Small-scale

0.647

High

725929

PSK1
Serine/threonine-protein kinase PSK1

1

17

High-throughput

0.647

High

735272

KNS1
Dual specificity protein kinase KNS1

1

15

Small-scale

0.647

High

735530

IRE1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

6

High-throughput

0.647

High

754232

MSN4
Zinc finger protein MSN4

1

5

Small-scale

0.647

High

800811

RCK2
Serine/threonine-protein kinase RCK2

1

17

High-throughput

0.647

High

801880

KSP1
Serine/threonine-protein kinase KSP1

1

18

High-throughput

0.647

High

865518

PTK2
Serine/threonine-protein kinase PTK2/STK2

1

14

High-throughput

0.647

High

923079

GIN4
Serine/threonine-protein kinase GIN4

1

17

Small-scale

0.647

High

393118

HSP82
ATP-dependent molecular chaperone HSP82

1

20

High-throughput

0.618

High

741040

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

13

High-throughput

0.618

High

744394

ATC5
Phospholipid-transporting ATPase DNF1

2

2

Small-scale

0.608

High

709902

BMH1
Protein BMH1

2

15

High-throughput

0.601

High

760314

BMH2
Protein BMH2

2

15

High-throughput

0.601

High

893280

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

2

13

Small-scale

0.584

High

923073

FPK1
Flippase kinase 1

1

18

Small-scale

0.575

High

711512

BEM1
Bud emergence protein 1

1

12

High-throughput

0.541

High

678120

SYP1
Suppressor of yeast profilin deletion

1

2

High-throughput

0.536

High

923078

SOG2
Leucine-rich repeat-containing protein SOG2

1

14

High-throughput

0.536

High

460740

CDC4
Cell division control protein 4

1

12

Small-scale

0.501

High

726014

NTH1
Endonuclease III homolog 1

1

2

Small-scale

0.501

High

746457

SSO1
Protein SSO1

1

5

Small-scale

0.501

High

758282

HCS1
DNA polymerase alpha-associated DNA helicase A

1

2

Small-scale

0.501

High

805562

SET1
Histone-lysine N-methyltransferase, H3 lysine-4 specific

1

4

Small-scale

0.501

High

814966

SSO2
Protein SSO2

1

5

Small-scale

0.501

High

822464

TBP6
Probable 26S proteasome subunit YTA6

1

9

Small-scale

0.501

High

923074

SLM2
Phosphatidylinositol 4,5-bisphosphate-binding protein SLM2

1

2

Small-scale

0.501

High

923075

TCB3
Tricalbin-3

1

6

Small-scale

0.501

High

923080

ATC8
Probable phospholipid-transporting ATPase DNF3

1

3

Small-scale

0.501

High

923081

ATC4
Phospholipid-transporting ATPase DNF2

1

1

Small-scale

0.501

High

626838

HSP60
Heat shock protein 60, mitochondrial

1

14

High-throughput

0.500

High

817810

NU157
Nucleoporin NUP157

1

1

High-throughput

0.489

High

575287

RAD9
DNA repair protein RAD9

1

0

Small-scale

0.480

High

794387

MAL33
Maltose fermentation regulatory protein MAL33

1

0

Small-scale

0.480

High

815860

TOG1
Transcription factor TOG1

1

0

Small-scale

0.480

High

850532

PTR3
SPS-sensor component PTR3

1

0

Small-scale

0.480

High

917092

MDS3
Negative regulator of sporulation MDS3

1

0

Small-scale

0.480

High

920751

SULX
Putative sulfate transporter YPR003C

1

0

Small-scale

0.480

High

923076

SEG1
Eisosome protein SEG1

1

0

Small-scale

0.480

High

555120

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.479

High

510703

HSP77
Import motor subunit, mitochondrial

1

17

High-throughput

0.479

High

594493

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

4

High-throughput

0.479

High

707799

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

798178

VHC1
Vacuolar cation-chloride cotransporter 1

1

3

High-throughput

0.470

High

923077

ATG13
Autophagy-related protein 13

1

1

Small-scale

0.457

High

545768

SSB1
Ribosome-associated molecular chaperone SSB1

1

13

High-throughput

0.445

High

819402

SSB2
Ribosome-associated molecular chaperone SSB2

1

13

High-throughput

0.445

High

824506

6P21
6-phosphofructo-2-kinase 1

1

11

High-throughput

0.445

High

850375

IOC3
ISWI one complex protein 3

1

0

High-throughput

0.279

Low

605916

HPR1
THO complex subunit HPR1

1

0

High-throughput

0.269

Low

763717

MTH1
Protein MTH1

1

0

Small-scale

0.261

Low

917018

CTU1
Cytoplasmic tRNA 2-thiolation protein 1

1

0

Small-scale

0.261

Low


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Last updated: 11Aug2025