Protein: MAST3
Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1)

Gene: MAST3
Organism: Homo sapiens
Interactions: 128
UniProt ID: O60307

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0007010 - cytoskeleton organization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

225501

AAKB2
5'-AMP-activated protein kinase subunit beta-2

1

2

High-throughput

0.691

High

245206

AAPK2
5'-AMP-activated protein kinase catalytic subunit alpha-2

1

17

High-throughput

0.691

High

245215

CSK2B
Casein kinase II subunit beta

1

5

High-throughput

0.691

High

245216

CSK21
Casein kinase II subunit alpha

1

20

High-throughput

0.691

High

245226

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

1

17

High-throughput

0.691

High

245259

LRC59
Leucine-rich repeat-containing protein 59

1

5

High-throughput

0.691

High

245299

AAKB1
5'-AMP-activated protein kinase subunit beta-1

1

2

High-throughput

0.691

High

245220

1433F
14-3-3 protein eta

4

20

High-throughput

0.687

High

245211

1433G
14-3-3 protein gamma

3

20

High-throughput

0.662

High

245188

IF2A
Eukaryotic translation initiation factor 2 subunit 1

1

3

High-throughput

0.618

High

245204

HNRPM
Heterogeneous nuclear ribonucleoprotein M

1

8

High-throughput

0.618

High

245227

ROA0
Heterogeneous nuclear ribonucleoprotein A0

1

11

High-throughput

0.618

High

245234

PSG3
Pregnancy-specific beta-1-glycoprotein 3

1

4

High-throughput

0.618

High

176787

DCLK1
Serine/threonine-protein kinase DCLK1

1

14

High-throughput

0.618

High

208602

SI1L1
Signal-induced proliferation-associated 1-like protein 1

1

2

High-throughput

0.618

High

230484

KIF1C
Kinesin-like protein KIF1C

1

3

High-throughput

0.618

High

245180

KIF1B
Kinesin-like protein KIF1B

1

3

High-throughput

0.618

High

245195

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

17

High-throughput

0.618

High

245200

MPIP2
M-phase inducer phosphatase 2

1

1

High-throughput

0.618

High

245201

MPIP3
M-phase inducer phosphatase 3

1

1

High-throughput

0.618

High

245218

CDK16
Cyclin-dependent kinase 16

1

11

High-throughput

0.618

High

245224

PTN13
Tyrosine-protein phosphatase non-receptor type 13

1

8

High-throughput

0.618

High

245230

MELK
Maternal embryonic leucine zipper kinase

1

16

High-throughput

0.618

High

245231

ZN638
Zinc finger protein 638

1

5

High-throughput

0.618

High

245235

M3K21
Mitogen-activated protein kinase kinase kinase 21

1

5

High-throughput

0.618

High

245247

RGPS2
Ras-specific guanine nucleotide-releasing factor RalGPS2

1

6

High-throughput

0.618

High

245248

KSR1
Kinase suppressor of Ras 1

1

12

High-throughput

0.618

High

245260

MAGI1
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1

1

18

High-throughput

0.618

High

245261

TESK2
Dual specificity testis-specific protein kinase 2

1

2

High-throughput

0.618

High

245276

KI13B
Kinesin-like protein KIF13B

1

3

High-throughput

0.618

High

245289

PPM1H
Protein phosphatase 1H

1

3

High-throughput

0.618

High

245292

GAB2
GRB2-associated-binding protein 2

1

6

High-throughput

0.618

High

245212

1433E
14-3-3 protein epsilon

2

13

High-throughput

0.611

High

245182

CCNT2
Cyclin-T2

1

9

High-throughput

0.553

High

245225

TIAM1
Rho guanine nucleotide exchange factor TIAM1

1

14

High-throughput

0.553

High

245238

AN34A
Ankyrin repeat domain-containing protein 34A

1

6

High-throughput

0.553

High

245239

PKHA7
Pleckstrin homology domain-containing family A member 7

1

20

High-throughput

0.553

High

245246

PHLB2
Pleckstrin homology-like domain family B member 2

1

14

High-throughput

0.553

High

245257

SRS12
Serine/arginine-rich splicing factor 12

1

10

High-throughput

0.553

High

245274

PKHA5
Pleckstrin homology domain-containing family A member 5

1

18

High-throughput

0.553

High

245288

ZBT21
Zinc finger and BTB domain-containing protein 21

1

3

High-throughput

0.553

High

245290

AGAP1
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1

1

12

High-throughput

0.553

High

245287

PNMA2
Paraneoplastic antigen Ma2

2

9

High-throughput

0.549

High

245208

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

3

Small-scale

0.549

High

143507

PPP6
Serine/threonine-protein phosphatase 6 catalytic subunit

1

15

High-throughput

0.536

High

240029

KPRB
Phosphoribosyl pyrophosphate synthase-associated protein 2

1

6

High-throughput

0.536

High

245189

ATPB
ATP synthase F(1) complex subunit beta, mitochondrial

1

4

High-throughput

0.536

High

245192

XRCC6
X-ray repair cross-complementing protein 6

1

3

High-throughput

0.536

High

245193

XRCC5
X-ray repair cross-complementing protein 5

1

3

High-throughput

0.536

High

245194

YBOX3
Y-box-binding protein 3

1

4

High-throughput

0.536

High

245196

DDX5
Probable ATP-dependent RNA helicase DDX5

1

7

High-throughput

0.536

High

245202

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.536

High

245205

AAKG1
5'-AMP-activated protein kinase subunit gamma-1

1

3

High-throughput

0.536

High

245210

RL37
Large ribosomal subunit protein eL37

1

1

High-throughput

0.536

High

245213

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.536

High

245214

RS21
Small ribosomal subunit protein eS21

1

2

High-throughput

0.536

High

245221

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

1

High-throughput

0.536

High

245232

PCBP1
Poly(rC)-binding protein 1

1

3

High-throughput

0.536

High

245244

ZCCHV
Zinc finger CCCH-type antiviral protein 1

1

5

High-throughput

0.536

High

245262

PKP2
Plakophilin-2

1

11

High-throughput

0.536

High

245269

EIF2A
Eukaryotic translation initiation factor 2A

1

4

High-throughput

0.536

High

245277

DDX21
Nucleolar RNA helicase 2

1

10

High-throughput

0.536

High

245294

DRG1
Developmentally-regulated GTP-binding protein 1

1

2

High-throughput

0.536

High

245298

PKP3
Plakophilin-3

1

11

High-throughput

0.536

High

245268

RTKN
Rhotekin

1

0

High-throughput

0.517

High

245275

TANC2
Protein TANC2

1

0

High-throughput

0.517

High

245280

LRFN1
Leucine-rich repeat and fibronectin type III domain-containing protein 1

1

0

High-throughput

0.517

High

245267

PYM1
Partner of Y14 and mago

1

0

High-throughput

0.513

High

245293

RTRAF
RNA transcription, translation and transport factor protein

1

0

High-throughput

0.513

High

229596

CALU
Calumenin

1

5

High-throughput

0.489

High

245187

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

13

High-throughput

0.489

High

245190

PARP1
Poly [ADP-ribose] polymerase 1

1

5

High-throughput

0.489

High

245209

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

1

High-throughput

0.489

High

245222

CKAP4
Cytoskeleton-associated protein 4

1

17

High-throughput

0.489

High

245228

TIF1B
Transcription intermediary factor 1-beta

1

9

High-throughput

0.489

High

245258

RT31
Small ribosomal subunit protein mS31

1

1

High-throughput

0.489

High

245181

IF4E2
Eukaryotic translation initiation factor 4E type 2

1

2

High-throughput

0.479

High

245191

BIP
Endoplasmic reticulum chaperone BiP

1

13

High-throughput

0.479

High

245197

IF2B
Eukaryotic translation initiation factor 2 subunit 2

1

4

High-throughput

0.479

High

245198

NF1
Neurofibromin

1

8

High-throughput

0.479

High

245199

COF1
Cofilin-1

1

1

High-throughput

0.479

High

245203

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

12

High-throughput

0.479

High

245207

HDAC4
Histone deacetylase 4

1

9

High-throughput

0.479

High

245217

VIGLN
Vigilin

1

4

High-throughput

0.479

High

245219

TF65
Transcription factor p65

1

12

High-throughput

0.479

High

245229

CUL3
Cullin-3

1

11

High-throughput

0.479

High

245233

PTN14
Tyrosine-protein phosphatase non-receptor type 14

1

7

High-throughput

0.479

High

245236

SPD2A
SH3 and PX domain-containing protein 2A

1

10

High-throughput

0.479

High

245240

LARP1
La-related protein 1

1

5

High-throughput

0.479

High

245249

RPTOR
Regulatory-associated protein of mTOR

1

9

High-throughput

0.479

High

245250

NAV1
Neuron navigator 1

1

3

High-throughput

0.479

High

245255

HDAC7
Histone deacetylase 7

1

8

High-throughput

0.479

High

245256

DEP1B
DEP domain-containing protein 1B

1

5

High-throughput

0.479

High

245263

SIN1
Target of rapamycin complex 2 subunit MAPKAP1

1

4

High-throughput

0.479

High

245273

SAV1
Protein salvador homolog 1

1

17

High-throughput

0.479

High

245283

XPO7
Exportin-7

1

8

High-throughput

0.479

High

245285

UBP21
Ubiquitin carboxyl-terminal hydrolase 21

1

7

High-throughput

0.479

High

245295

FBW1A
F-box/WD repeat-containing protein 1A

1

11

High-throughput

0.479

High

245272

CNTP4
Contactin-associated protein-like 4

1

2

Small-scale

0.464

High

245183

SRGP2
SLIT-ROBO Rho GTPase-activating protein 2

1

0

High-throughput

0.458

High

245186

NADK
NAD kinase

1

0

High-throughput

0.458

High

245185

GGYF1
GRB10-interacting GYF protein 1

1

5

High-throughput

0.437

High

245223

CAMP2
Calmodulin-regulated spectrin-associated protein 2

1

14

High-throughput

0.437

High

245237

DEN4C
DENN domain-containing protein 4C

1

5

High-throughput

0.437

High

245241

GGYF2
GRB10-interacting GYF protein 2

1

14

High-throughput

0.437

High

245242

SYDE1
Rho GTPase-activating protein SYDE1

1

6

High-throughput

0.437

High

245243

RFIP2
Rab11 family-interacting protein 2

1

11

High-throughput

0.437

High

245245

MYCPP
C-myc promoter-binding protein

1

5

High-throughput

0.437

High

245251

F110B
Protein FAM110B

1

2

High-throughput

0.437

High

245252

RBCC1
RB1-inducible coiled-coil protein 1

1

20

High-throughput

0.437

High

245253

DEN1A
DENN domain-containing protein 1A

1

5

High-throughput

0.437

High

245254

SH3R3
E3 ubiquitin-protein ligase SH3RF3

1

13

High-throughput

0.437

High

245264

F110A
Protein FAM110A

1

2

High-throughput

0.437

High

245266

LPIN3
Phosphatidate phosphatase LPIN3

1

2

High-throughput

0.437

High

245270

ACE2
Angiotensin-converting enzyme 2

1

2

Small-scale

0.437

High

245271

OSBL6
Oxysterol-binding protein-related protein 6

1

3

High-throughput

0.437

High

245278

INP5E
Phosphatidylinositol polyphosphate 5-phosphatase type IV

1

1

High-throughput

0.437

High

245281

CING
Cingulin

1

12

High-throughput

0.437

High

245282

LIMA1
LIM domain and actin-binding protein 1

1

5

High-throughput

0.437

High

245284

NGAP
Ras GTPase-activating protein nGAP

1

8

High-throughput

0.437

High

245286

FBW1B
F-box/WD repeat-containing protein 11

1

10

High-throughput

0.437

High

245291

UBP24
Ubiquitin carboxyl-terminal hydrolase 24

1

9

High-throughput

0.437

High

245297

STA13
StAR-related lipid transfer protein 13

1

9

High-throughput

0.437

High

245300

KCTD3
BTB/POZ domain-containing protein KCTD3

1

7

High-throughput

0.437

High

245265

APOL2
Apolipoprotein L2

1

0

High-throughput

0.279

Low

245184

TULP3
Tubby-related protein 3

1

0

High-throughput

0.249

Low

245279

FA53C
Protein FAM53C

1

0

High-throughput

0.249

Low

245296

CBY1
Protein chibby homolog 1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025