Interactor 1: VINEX (O60504)
Vinexin (SH3-containing adapter molecule 1) (SCAM-1) (Sorbin and SH3 domain-containing protein 3)
Gene: SORBS3

Interactor 2: NOTC3 (Q9UM47)
Neurogenic locus notch homolog protein 3 (Notch 3) [Cleaved into: Notch 3 extracellular truncation; Notch 3 intracellular domain]
Gene: NOTCH3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 25356737
Identification Methods pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Ank_2~SH3_1, Ank_2~SH3_9
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005829 - cytosol
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 671
Hs

1 2321
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024