Interactor 1: BUB1B (O60566)
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (MAD3/BUB1-related protein kinase) (hBUBR1) (Mitotic checkpoint kinase MAD3L) (Protein SSK1)
Gene: BUB1B

Interactor 2: CDC27 (P30260)
Cell division cycle protein 27 homolog (Anaphase-promoting complex subunit 3) (APC3) (CDC27 homolog) (CDC27Hs) (H-NUC)
Gene: CDC27

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 0.60 0.767

The method score is based on:

Property Details
Experiments 25246557, 22193957, 25306918, 26811472, 27114510, 29432156, 30341343, 32152539, 32076268, 18722180, 21926987, 22100920, 23007861, 23754430, 25852190, 25673878, 33961781, 10477750, 32707033, 20360068 and 5 others

more...

Identification Methods pull down, affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005680 - anaphase-promoting complex
GO:0005737 - cytoplasm
GO:0005813 - centrosome
GO:0005819 - spindle
and 3 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 1050
Hs

1 824
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Sc
+ Sp
+ Hs
+ Sp
+ Hs
+ Hs
+ Hs
+ Hs
+ Rn
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024