Download interactions: TXT MITAB-2.5
| Interaction | Interactor | Experiments | Homologs | Category | Interaction Score |
Confidence |
|---|---|---|---|---|---|---|
|
SOCS1
Suppressor of cytokine signaling 1 |
16 |
20 |
Small-scale |
0.984 | High |
|
|
SOCS3
Suppressor of cytokine signaling 3 |
12 |
20 |
Small-scale |
0.979 | High |
|
|
STAT3
Signal transducer and activator of transcription 3 |
11 |
20 |
Small-scale |
0.972 | High |
|
|
JAK2
Tyrosine-protein kinase JAK2 |
9 |
19 |
Small-scale |
0.967 | High |
|
|
SH2B1
SH2B adapter protein 1 |
5 |
20 |
Small-scale |
0.934 | High |
|
|
EGFR
Epidermal growth factor receptor |
5 |
20 |
Small-scale |
0.912 | High |
|
|
PTN1
Tyrosine-protein phosphatase non-receptor type 1 |
4 |
20 |
Small-scale |
0.900 | High |
|
|
PTN11
Tyrosine-protein phosphatase non-receptor type 11 |
4 |
20 |
Small-scale |
0.890 | High |
|
|
STA5A
Signal transducer and activator of transcription 5A |
4 |
20 |
Small-scale |
0.888 | High |
|
|
GRB2
Growth factor receptor-bound protein 2 |
4 |
20 |
Small-scale |
0.882 | High |
|
|
STAT1
Signal transducer and activator of transcription 1-alpha/beta |
4 |
20 |
Small-scale |
0.881 | High |
|
|
GHR
Growth hormone receptor |
4 |
20 |
Small-scale |
0.873 | High |
|
|
EPOR
Erythropoietin receptor |
3 |
20 |
Small-scale |
0.861 | High |
|
|
P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha |
3 |
20 |
Small-scale |
0.861 | High |
|
|
STA5B
Signal transducer and activator of transcription 5B |
3 |
20 |
Small-scale |
0.835 | High |
|
|
IRS1
Insulin receptor substrate 1 |
3 |
20 |
Small-scale |
0.834 | High |
|
|
VAV
Proto-oncogene vav |
2 |
20 |
Small-scale |
0.806 | High |
|
|
SHC1
SHC-transforming protein 1 |
2 |
20 |
Small-scale |
0.778 | High |
|
|
PTN6
Tyrosine-protein phosphatase non-receptor type 6 |
2 |
20 |
Small-scale |
0.776 | High |
|
|
M3K5
Mitogen-activated protein kinase kinase kinase 5 |
1 |
20 |
Small-scale |
0.770 | High |
|
|
JAK1
Tyrosine-protein kinase JAK1 |
2 |
19 |
Small-scale |
0.768 | High |
|
|
TEC
Tyrosine-protein kinase Tec |
2 |
20 |
Small-scale |
0.768 | High |
|
|
SH2B2
SH2B adapter protein 2 |
2 |
20 |
Small-scale |
0.755 | High |
|
|
INSR
Insulin receptor |
2 |
20 |
Small-scale |
0.754 | High |
|
|
PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 |
2 |
20 |
Small-scale |
0.754 | High |
|
|
FAK1
Focal adhesion kinase 1 |
2 |
20 |
Small-scale |
0.754 | High |
|
|
FYN
Tyrosine-protein kinase Fyn |
1 |
19 |
Small-scale |
0.724 | High |
|
|
STAM1
Signal transducing adapter molecule 1 |
1 |
20 |
Small-scale |
0.724 | High |
|
|
I12R2
Interleukin-12 receptor subunit beta-2 |
1 |
20 |
Small-scale |
0.724 | High |
|
|
IL3RB
Cytokine receptor common subunit beta |
5 |
20 |
Small-scale |
0.711 | High |
|
|
SRC
Proto-oncogene tyrosine-protein kinase Src |
1 |
19 |
Small-scale |
0.691 | High |
|
|
TOPK
Lymphokine-activated killer T-cell-originated protein kinase |
1 |
5 |
High-throughput |
0.691 | High |
|
|
JAK3
Tyrosine-protein kinase JAK3 |
1 |
19 |
Small-scale |
0.665 | High |
|
|
RAF1
RAF proto-oncogene serine/threonine-protein kinase |
1 |
20 |
Small-scale |
0.647 | High |
|
|
LYN
Tyrosine-protein kinase Lyn |
1 |
19 |
Small-scale |
0.647 | High |
|
|
ERBB3
Receptor tyrosine-protein kinase erbB-3 |
1 |
20 |
High-throughput |
0.647 | High |
|
|
ANM5
Protein arginine N-methyltransferase 5 |
2 |
12 |
Small-scale |
0.644 | High |
|
|
TNR1A
Tumor necrosis factor receptor superfamily member 1A |
2 |
20 |
Small-scale |
0.634 | High |
|
|
UBIP1
Upstream-binding protein 1 |
2 |
3 |
High-throughput |
0.628 | High |
|
|
UN13B
Protein unc-13 homolog B |
1 |
20 |
High-throughput |
0.618 | High |
|
|
ROCK2
Rho-associated protein kinase 2 |
1 |
20 |
Small-scale |
0.618 | High |
|
|
STAM2
Signal transducing adapter molecule 2 |
1 |
20 |
Small-scale |
0.618 | High |
|
|
ERBB2
Receptor tyrosine-protein kinase erbB-2 |
1 |
20 |
Small-scale |
0.618 | High |
|
|
HS90A
Heat shock protein HSP 90-alpha |
1 |
20 |
Small-scale |
0.618 | High |
|
|
IGF1R
Insulin-like growth factor 1 receptor |
1 |
20 |
Small-scale |
0.618 | High |
|
|
HS90B
Heat shock protein HSP 90-beta |
1 |
20 |
Small-scale |
0.618 | High |
|
|
KIT
Mast/stem cell growth factor receptor Kit |
1 |
20 |
Small-scale |
0.618 | High |
|
|
FGFR1
Fibroblast growth factor receptor 1 |
1 |
20 |
Small-scale |
0.618 | High |
|
|
NCK1
SH2/SH3 adapter protein NCK1 |
1 |
20 |
High-throughput |
0.618 | High |
|
|
PLCG2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 |
1 |
20 |
Small-scale |
0.618 | High |
|
|
TYK2
Non-receptor tyrosine-protein kinase TYK2 |
1 |
20 |
Small-scale |
0.618 | High |
|
|
IL6RB
Interleukin-6 receptor subunit beta |
1 |
20 |
Small-scale |
0.618 | High |
|
|
1433G
14-3-3 protein gamma |
1 |
20 |
High-throughput |
0.618 | High |
|
|
1433E
14-3-3 protein epsilon |
1 |
8 |
High-throughput |
0.618 | High |
|
|
PTN12
Tyrosine-protein phosphatase non-receptor type 12 |
1 |
20 |
Small-scale |
0.618 | High |
|
|
GRB10
Growth factor receptor-bound protein 10 |
1 |
20 |
Small-scale |
0.618 | High |
|
|
FAK2
Protein-tyrosine kinase 2-beta |
1 |
20 |
Small-scale |
0.618 | High |
|
|
SOCS4
Suppressor of cytokine signaling 4 |
1 |
20 |
Small-scale |
0.618 | High |
|
|
ALK
ALK tyrosine kinase receptor |
1 |
20 |
Small-scale |
0.618 | High |
|
|
SH2B3
SH2B adapter protein 3 |
1 |
20 |
Small-scale |
0.618 | High |
|
|
IL2RG
Cytokine receptor common subunit gamma |
2 |
20 |
Small-scale |
0.601 | High |
|
|
IL5RA
Interleukin-5 receptor subunit alpha |
1 |
20 |
Small-scale |
0.586 | High |
|
|
INGR1
Interferon gamma receptor 1 |
2 |
19 |
Small-scale |
0.584 | High |
|
|
PRLR
Prolactin receptor |
2 |
20 |
Small-scale |
0.584 | High |
|
|
TPOR
Thrombopoietin receptor |
2 |
7 |
Small-scale |
0.584 | High |
|
|
CBL
E3 ubiquitin-protein ligase CBL |
1 |
20 |
Small-scale |
0.578 | High |
|
|
CDN1B
Cyclin-dependent kinase inhibitor 1B |
1 |
7 |
Small-scale |
0.578 | High |
|
|
LEPR
Leptin receptor |
1 |
20 |
Small-scale |
0.575 | High |
|
|
PTPRJ
Receptor-type tyrosine-protein phosphatase eta |
1 |
20 |
High-throughput |
0.575 | High |
|
|
NEMO
NF-kappa-B essential modulator |
1 |
20 |
High-throughput |
0.561 | High |
|
|
VHL
von Hippel-Lindau disease tumor suppressor |
2 |
0 |
Small-scale |
0.559 | High |
|
|
RBMX
RNA-binding motif protein, X chromosome |
1 |
11 |
High-throughput |
0.541 | High |
|
|
ARL11
ADP-ribosylation factor-like protein 11 |
1 |
15 |
High-throughput |
0.541 | High |
|
|
BACH1
Transcription regulator protein BACH1 |
1 |
5 |
High-throughput |
0.536 | High |
|
|
HMMR
Hyaluronan mediated motility receptor |
1 |
20 |
High-throughput |
0.536 | High |
|
|
GTR1
Solute carrier family 2, facilitated glucose transporter member 1 |
1 |
3 |
High-throughput |
0.536 | High |
|
|
EMD
Emerin |
1 |
3 |
High-throughput |
0.536 | High |
|
|
NP1L1
Nucleosome assembly protein 1-like 1 |
1 |
7 |
High-throughput |
0.536 | High |
|
|
IMB1
Importin subunit beta-1 |
1 |
10 |
High-throughput |
0.536 | High |
|
|
RHG18
Rho GTPase-activating protein 18 |
1 |
20 |
High-throughput |
0.536 | High |
|
|
MUC7
Mucin-7 |
1 |
17 |
High-throughput |
0.536 | High |
|
|
MUC5B
Mucin-5B |
1 |
15 |
High-throughput |
0.536 | High |
|
|
SPRR3
Small proline-rich protein 3 |
1 |
3 |
High-throughput |
0.536 | High |
|
|
CISH
Cytokine-inducible SH2-containing protein |
1 |
20 |
Small-scale |
0.527 | High |
|
|
ASSY
Argininosuccinate synthase |
1 |
0 |
High-throughput |
0.518 | High |
|
|
HSFY1
Heat shock transcription factor, Y-linked |
1 |
0 |
High-throughput |
0.518 | High |
|
|
IL4RA
Interleukin-4 receptor subunit alpha |
1 |
20 |
Small-scale |
0.515 | High |
|
|
BRCA1
Breast cancer type 1 susceptibility protein |
1 |
14 |
Small-scale |
0.515 | High |
|
|
CXCR4
C-X-C chemokine receptor type 4 |
1 |
18 |
Small-scale |
0.515 | High |
|
|
DNJA3
DnaJ homolog subfamily A member 3, mitochondrial |
1 |
13 |
Small-scale |
0.515 | High |
|
|
IGJ
Immunoglobulin J chain |
1 |
0 |
High-throughput |
0.513 | High |
|
|
CYTT
Cystatin-SA |
1 |
0 |
High-throughput |
0.513 | High |
|
|
PAUF
Pancreatic adenocarcinoma up-regulated factor |
1 |
0 |
High-throughput |
0.513 | High |
|
|
PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit |
1 |
8 |
Small-scale |
0.508 | High |
|
|
INGR2
Interferon gamma receptor 2 |
1 |
20 |
Small-scale |
0.501 | High |
|
|
TUB
Tubby protein homolog |
1 |
7 |
Small-scale |
0.501 | High |
|
|
TERA
Transitional endoplasmic reticulum ATPase |
1 |
4 |
Small-scale |
0.501 | High |
|
|
GTF2I
General transcription factor II-I |
1 |
2 |
Small-scale |
0.501 | High |
|
|
EZH2
Histone-lysine N-methyltransferase EZH2 |
1 |
8 |
Small-scale |
0.501 | High |
|
|
H31T
Histone H3.1t |
1 |
4 |
Small-scale |
0.501 | High |
|
|
RCN1
Reticulocalbin-1 |
1 |
3 |
High-throughput |
0.489 | High |
|
|
BPIA2
BPI fold-containing family A member 2 |
1 |
1 |
High-throughput |
0.489 | High |
|
|
TRAF6
TNF receptor-associated factor 6 |
1 |
20 |
High-throughput |
0.481 | High |
|
|
LDOC1
Protein LDOC1 |
1 |
1 |
Small-scale |
0.479 | High |
|
|
TRFE
Serotransferrin |
1 |
2 |
High-throughput |
0.479 | High |
|
|
HSP7C
Heat shock cognate 71 kDa protein |
1 |
20 |
Small-scale |
0.479 | High |
|
|
IL2RB
Interleukin-2 receptor subunit beta |
1 |
20 |
Small-scale |
0.479 | High |
|
|
CTLA4
Cytotoxic T-lymphocyte protein 4 |
1 |
5 |
Small-scale |
0.479 | High |
|
|
TSHR
Thyrotropin receptor |
1 |
20 |
Small-scale |
0.479 | High |
|
|
PTAFR
Platelet-activating factor receptor |
1 |
20 |
Small-scale |
0.479 | High |
|
|
5HT2A
5-hydroxytryptamine receptor 2A |
1 |
10 |
Small-scale |
0.479 | High |
|
|
2AAB
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform |
1 |
9 |
Small-scale |
0.479 | High |
|
|
AGTR1
Type-1 angiotensin II receptor |
1 |
18 |
Small-scale |
0.479 | High |
|
|
CCR5
C-C chemokine receptor type 5 |
1 |
19 |
Small-scale |
0.479 | High |
|
|
PPIA
Peptidyl-prolyl cis-trans isomerase A |
1 |
8 |
Small-scale |
0.479 | High |
|
|
SHPS1
Tyrosine-protein phosphatase non-receptor type substrate 1 |
1 |
9 |
Small-scale |
0.479 | High |
|
|
G3BP1
Ras GTPase-activating protein-binding protein 1 |
1 |
11 |
Small-scale |
0.479 | High |
|
|
SKP2
S-phase kinase-associated protein 2 |
1 |
19 |
Small-scale |
0.479 | High |
|
|
CUL4A
Cullin-4A |
1 |
12 |
High-throughput |
0.479 | High |
|
|
CUL4B
Cullin-4B |
1 |
12 |
High-throughput |
0.479 | High |
|
|
HES1
Transcription factor HES-1 |
1 |
2 |
Small-scale |
0.479 | High |
|
|
JOS1
Josephin-1 |
1 |
1 |
Small-scale |
0.479 | High |
|
|
EEA1
Early endosome antigen 1 |
1 |
16 |
High-throughput |
0.479 | High |
|
|
CCDC6
Coiled-coil domain-containing protein 6 |
1 |
20 |
High-throughput |
0.479 | High |
|
|
HES5
Transcription factor HES-5 |
1 |
2 |
Small-scale |
0.479 | High |
|
|
RN123
E3 ubiquitin-protein ligase RNF123 |
1 |
9 |
High-throughput |
0.479 | High |
|
|
ELP2
Elongator complex protein 2 |
1 |
9 |
Small-scale |
0.479 | High |
|
|
H32
Histone H3.2 |
1 |
4 |
Small-scale |
0.479 | High |
|
|
PARP9
Protein mono-ADP-ribosyltransferase PARP9 |
1 |
8 |
Small-scale |
0.479 | High |
|
|
LNX1
E3 ubiquitin-protein ligase LNX |
1 |
20 |
Small-scale |
0.479 | High |
|
|
DTX3L
E3 ubiquitin-protein ligase DTX3L |
1 |
9 |
Small-scale |
0.479 | High |
|
|
UBP33
Ubiquitin carboxyl-terminal hydrolase 33 |
1 |
20 |
Small-scale |
0.479 | High |
|
|
OPTN
Optineurin |
1 |
20 |
Small-scale |
0.479 | High |
|
|
ASB2
Ankyrin repeat and SOCS box protein 2 |
1 |
18 |
Small-scale |
0.479 | High |
|
|
STRA6
Receptor for retinol uptake STRA6 |
1 |
1 |
Small-scale |
0.479 | High |
|
|
CLSPN
Claspin |
1 |
5 |
High-throughput |
0.479 | High |
|
|
HDAC6
Protein deacetylase HDAC6 |
1 |
8 |
Small-scale |
0.479 | High |
|
|
RASF2
Ras association domain-containing protein 2 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
GOLP3
Golgi phosphoprotein 3 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
IGHA2
Immunoglobulin heavy constant alpha 2 |
1 |
14 |
High-throughput |
0.445 | High |
|
|
BROX
BRO1 domain-containing protein BROX |
1 |
8 |
High-throughput |
0.437 | High |
|
|
AMY1B
Alpha-amylase 1B |
1 |
1 |
High-throughput |
0.407 | High |
Service provided by Combinatics, Japan
Last updated: 11Aug2025
