Protein: TNK1
Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1)

Gene: TNK1
Organism: Homo sapiens
Interactions: 44
UniProt ID: Q13470

Gene Ontology (top 5):
GO:0004713 - protein tyrosine kinase activity
GO:0004715 - non-membrane spanning protein tyrosine kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

971488

1433E
14-3-3 protein epsilon

3

8

High-throughput

0.861

High

730566

1433S
14-3-3 protein sigma

3

20

High-throughput

0.855

High

690979

1433T
14-3-3 protein theta

2

20

High-throughput

0.811

High

729806

1433B
14-3-3 protein beta/alpha

2

20

High-throughput

0.811

High

966278

1433G
14-3-3 protein gamma

2

20

High-throughput

0.811

High

990187

1433Z
14-3-3 protein zeta/delta

2

20

High-throughput

0.811

High

1049261

1433F
14-3-3 protein eta

2

20

High-throughput

0.811

High

1102319

GRB10
Growth factor receptor-bound protein 10

2

20

High-throughput

0.783

High

171698

GAK
Cyclin-G-associated kinase

1

20

High-throughput

0.691

High

593360

PGFRA
Platelet-derived growth factor receptor alpha

1

20

High-throughput

0.691

High

619052

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

18

Small-scale

0.647

High

1106401

TNK1
Non-receptor tyrosine-protein kinase TNK1

1

20

Small-scale

0.647

High

461444

HS90A
Heat shock protein HSP 90-alpha

1

20

High-throughput

0.618

High

468339

HS90B
Heat shock protein HSP 90-beta

1

20

High-throughput

0.618

High

1106403

CDC37
Hsp90 co-chaperone Cdc37

1

16

High-throughput

0.618

High

273998

CREST
Calcium-responsive transactivator

2

7

High-throughput

0.553

High

585030

ZN250
Zinc finger protein 250

2

5

High-throughput

0.553

High

1106404

ZN329
Zinc finger protein 329

2

8

High-throughput

0.553

High

485120

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

15

High-throughput

0.536

High

608580

DDX5
Probable ATP-dependent RNA helicase DDX5

1

5

High-throughput

0.536

High

666095

PPAC
Low molecular weight phosphotyrosine protein phosphatase

1

4

High-throughput

0.536

High

846281

MATR3
Matrin-3

1

4

High-throughput

0.536

High

938714

HNRH2
Heterogeneous nuclear ribonucleoprotein H2

1

11

High-throughput

0.536

High

1026014

CLH1
Clathrin heavy chain 1

1

10

High-throughput

0.536

High

1089635

ILF3
Interleukin enhancer-binding factor 3

1

11

High-throughput

0.536

High

1100751

G3BP1
Ras GTPase-activating protein-binding protein 1

1

7

High-throughput

0.536

High

1106406

NIN
Ninein

1

20

High-throughput

0.536

High

1106407

DDX1
ATP-dependent RNA helicase DDX1

1

5

High-throughput

0.536

High

1106409

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

11

High-throughput

0.536

High

1106412

GTSE1
G2 and S phase-expressed protein 1

1

1

High-throughput

0.536

High

239054

ZNRD2
Protein ZNRD2

1

0

High-throughput

0.513

High

507928

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

9

High-throughput

0.501

High

175028

SC16A
Protein transport protein Sec16A

1

20

High-throughput

0.489

High

1106410

FAF2
FAS-associated factor 2

1

1

High-throughput

0.489

High

1106411

NFIP1
NEDD4 family-interacting protein 1

1

4

High-throughput

0.489

High

65572

TBAL3
Tubulin alpha chain-like 3

1

17

High-throughput

0.479

High

761666

HSP74
Heat shock 70 kDa protein 4

1

20

High-throughput

0.479

High

542767

G6PD
Glucose-6-phosphate 1-dehydrogenase

1

0

High-throughput

0.458

High

1106402

HERP1
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein

1

0

High-throughput

0.458

High

76521

B4DYC6
cDNA FLJ60958, highly similar to Homo sapiens SGT1, suppressor of G2 allele of SKP1

1

3

High-throughput

0.437

High

429837

JUN
Transcription factor Jun

1

5

High-throughput

0.407

High

1106405

SAXO1
Stabilizer of axonemal microtubules 1

2

0

High-throughput

0.316

High

1106408

F168A
Protein FAM168A

2

0

High-throughput

0.316

High


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Last updated: 11Aug2025