HitPredict

Interactor 1: PLOD3 (O60568)
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 [Includes: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 (EC 1.14.11.4) (Lysyl hydroxylase 3) (LH3); Procollagen glycosyltransferase (EC 2.4.1.50) (EC 2.4.1.66) (Galactosylhydroxylysine-glucosyltransferase) (Procollagen galactosyltransferase) (Procollagen glucosyltransferase)]
Gene: PLOD3

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35563538, 21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005794 - Golgi apparatus GO:0070062 - extracellular exosome
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 738 Hs			1 768
+	Hs
		972735 PLOD1_HUMAN (32-738): 0: 1184: 59.38		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		972736 PLOD1_HUMAN (32-738): 0: 1184: 59.38		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		972733 PLOD1_HUMAN (32-738): 0: 1184: 59.38		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Hs
		972734 PLOD1_HUMAN (32-738): 0: 1184: 59.38		CUL2_HUMAN (30-768): 0: 672: 26.17
+	Hs
		972799 PLOD1_HUMAN (32-738): 0: 1184: 59.38		CUL5_HUMAN (25-768): 0: 597: 23.77
+	Hs
		1042059 GT251_HUMAN (279-546): 1.17e-98: 319: 21.74		CUL3_HUMAN (1-768): 0: 951: 100.00