HitPredict

Interactor 1: PLOD3 (O60568)
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 [Includes: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 (EC 1.14.11.4) (Lysyl hydroxylase 3) (LH3); Procollagen glycosyltransferase (EC 2.4.1.50) (EC 2.4.1.66) (Galactosylhydroxylysine-glucosyltransferase) (Procollagen galactosyltransferase) (Procollagen glucosyltransferase)]
Gene: PLOD3

Interactor 2: COL10 (Q9Y6Z7)
Collectin-10 (Collectin liver protein 1) (CL-L1) (Collectin-34) (CL-34)
Gene: COLEC10

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005615 - extracellular space GO:0005794 - Golgi apparatus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 738 Hs			1 277
+	Hs
		237116 PLOD3_HUMAN (1-738): 0: 1310: 100.00		COL11_HUMAN (8-275): 6.2e-62: 198: 47.58
+	Hs
		129956 PLOD2_HUMAN (19-738): 0: 1217: 58.75		COL10_HUMAN (1-277): 3.62e-67: 211: 100.00
+	Hs
		129938 PLOD2_HUMAN (19-738): 0: 1217: 58.75		COL11_HUMAN (8-275): 6.2e-62: 198: 47.58
+	Hs
		237139 PLOD3_HUMAN (1-738): 0: 1310: 100.00		COHA1_HUMAN (45-116): 4.8e-11: 65.1: 51.39
+	Hs
		237006 PLOD3_HUMAN (1-738): 0: 1310: 100.00		CO4A1_HUMAN (45-116): 5.96e-11: 64.7: 48.61
+	Hs
		237016 PLOD3_HUMAN (1-738): 0: 1310: 100.00		CO4A2_HUMAN (46-118): 2.39e-10: 62.8: 48.10
+	Hs
		237019 PLOD3_HUMAN (1-738): 0: 1310: 100.00		CO6A1_HUMAN (28-116): 2.15e-10: 62.8: 41.57
+	Hs
		237054 PLOD3_HUMAN (1-738): 0: 1310: 100.00		CO9A2_HUMAN (46-122): 2.24e-10: 62.8: 42.39
+	Hs
		237020 PLOD3_HUMAN (1-738): 0: 1310: 100.00		CO6A2_HUMAN (46-122): 1.39e-09: 60.5: 37.90
+	Hs
		70492 PLOD3_HUMAN (1-738): 0: 1310: 100.00		C1T9B_HUMAN (47-122): 5.32e-09: 58.2: 44.71
+	Hs
		129885 PLOD2_HUMAN (19-738): 0: 1217: 58.75		CO6A2_HUMAN (46-122): 1.39e-09: 60.5: 37.90
+	Hs
		70491 PLOD2_HUMAN (19-738): 0: 1217: 58.75		C1T9B_HUMAN (47-122): 5.32e-09: 58.2: 44.71
+	Hs
		358661 PLOD1_HUMAN (32-738): 0: 1184: 59.38		CO4A1_HUMAN (45-116): 5.96e-11: 64.7: 48.61
+	Hs
		441060 PLOD1_HUMAN (32-738): 0: 1184: 59.38		CO4A2_HUMAN (46-118): 2.39e-10: 62.8: 48.10
+	Hs
		517941 PLOD1_HUMAN (32-738): 0: 1184: 59.38		CO6A1_HUMAN (28-116): 2.15e-10: 62.8: 41.57
+	Hs
		517998 PLOD1_HUMAN (32-738): 0: 1184: 59.38		CO6A2_HUMAN (46-122): 1.39e-09: 60.5: 37.90
+	Dm
		435988 PLOD_DROME (37-738): 0: 1033: 46.03		CO4A1_DROME (46-116): 6.04e-09: 58.5: 43.66
+	Hs
		518024 GT251_HUMAN (279-546): 1.17e-98: 319: 21.74		CO6A2_HUMAN (46-122): 1.39e-09: 60.5: 37.90
+	Hs
		70528 GT251_HUMAN (279-546): 1.17e-98: 319: 21.74		C1T9B_HUMAN (47-122): 5.32e-09: 58.2: 44.71
+	Hs
		70527 GT252_HUMAN (283-546): 5.69e-96: 312: 27.80		C1T9B_HUMAN (47-122): 5.32e-09: 58.2: 44.71