HitPredict

Interactor 1: IF4E2 (O60573)
Eukaryotic translation initiation factor 4E type 2 (eIF-4E type 2) (eIF4E type 2) (Eukaryotic translation initiation factor 4E homologous protein) (Eukaryotic translation initiation factor 4E-like 3) (eIF4E-like protein 4E-LP) (mRNA cap-binding protein 4EHP) (h4EHP) (mRNA cap-binding protein type 3)
Gene: EIF4E2

Interactor 2: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.697

Property	Details
Experiments	33961781, 35271311, 36931259, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 245 Hs			1 247
+	Hs
		237193 IF4E2_HUMAN (1-245): 5.31e-141: 396: 100.00		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		237203 IF4E2_HUMAN (1-245): 5.31e-141: 396: 100.00		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Hs
		237173 IF4E2_HUMAN (1-245): 5.31e-141: 396: 100.00		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		237194 IF4E2_HUMAN (1-245): 5.31e-141: 396: 100.00		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		237167 IF4E2_HUMAN (1-245): 5.31e-141: 396: 100.00		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33