Interactor 1: TLR2 (O60603)
Toll-like receptor 2 (Toll/interleukin-1 receptor-like protein 4) (CD antigen CD282)
Gene: TLR2

Interactor 2: CLC4M (Q9H2X3)
C-type lectin domain family 4 member M (CD209 antigen-like protein 1) (DC-SIGN-related protein) (DC-SIGNR) (Dendritic cell-specific ICAM-3-grabbing non-integrin 2) (DC-SIGN2) (Liver/lymph node-specific ICAM-3-grabbing non-integrin) (L-SIGN) (CD antigen CD299)
Gene: CLEC4M

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 21899704
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains LRR_8~Lectin_C
Common GO terms GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0006955 - immune response
GO:0038023 - signaling receptor activity
GO:0045087 - innate immune response
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 784
Hs

1 399
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024