HitPredict

Interactor 1: IMA7 (O60684)
Importin subunit alpha-7 (Karyopherin subunit alpha-6)
Gene: KPNA6

Interactor 2: CHD4 (Q14839)
Chromodomain-helicase-DNA-binding protein 4 (CHD-4) (EC 3.6.4.12) (ATP-dependent helicase CHD4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta)
Gene: CHD4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	28977666, 21555454
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 536 Hs			1 1912
+	Hs
		134899 IMA3_HUMAN (4-536): 9.52e-152: 446: 47.10		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		168636 IMA6_HUMAN (1-536): 3.72e-149: 440: 83.67		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		853602 IMA5_HUMAN (4-536): 1.39e-146: 433: 80.11		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		853286 IMA1_HUMAN (1-536): 5.59e-142: 421: 44.92		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		131423 IMA4_HUMAN (4-536): 4.93e-148: 436: 45.98		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		853580 IMA5_HUMAN (4-536): 1.39e-146: 433: 80.11		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		853257 IMA1_HUMAN (1-536): 5.59e-142: 421: 44.92		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Dm
		283986 O76522_DROME (10-536): 4.68e-140: 416: 44.59		CHDM_DROME (1-1904): 0: 1364: 50.85
+	Hs
		229344 IMA5_HUMAN (4-536): 1.39e-146: 433: 80.11		SMCA5_HUMAN (578-1624): 0: 791: 26.01
+	Hs
		238743 IMA7_HUMAN (1-536): 7e-160: 467: 100.00		CHD8_HUMAN (489-1678): 0: 752: 28.31
+	Hs
		658643 IMA5_HUMAN (4-536): 1.39e-146: 433: 80.11		SMCA1_HUMAN (617-1597): 0: 779: 27.44
+	Mm
		192636 IMA4_MOUSE (4-536): 9.19e-150: 441: 46.36		CHD8_MOUSE (254-1678): 0: 761: 25.10
+	Hs
		134969 IMA3_HUMAN (4-536): 9.52e-152: 446: 47.10		CHD8_HUMAN (489-1678): 0: 752: 28.31
+	Hs
		168673 IMA6_HUMAN (1-536): 3.72e-149: 440: 83.67		CHD8_HUMAN (489-1678): 0: 752: 28.31
+	Mm
		1000155 IMA5_MOUSE (4-536): 4.03e-145: 429: 79.74		CHD8_MOUSE (254-1678): 0: 761: 25.10
+	Hs
		853720 IMA5_HUMAN (4-536): 1.39e-146: 433: 80.11		CHD8_HUMAN (489-1678): 0: 752: 28.31
+	Mm
		853539 IMA1_MOUSE (1-536): 1.61e-140: 418: 45.10		CHD8_MOUSE (254-1678): 0: 761: 25.10
+	Hs
		853480 IMA1_HUMAN (1-536): 5.59e-142: 421: 44.92		CHD8_HUMAN (489-1678): 0: 752: 28.31
+	Zm
		11289 A0A1D6FC42_MAIZE (3-536): 4.91e-151: 444: 53.79		A0A1D6IBX9_MAIZE (319-420): 7.71e-11: 69.8: 34.29
+	Zm
		12493 A0A1D6FMC0_MAIZE (3-536): 2.82e-148: 439: 50.09		A0A1D6IBX9_MAIZE (319-420): 7.71e-11: 69.8: 34.29