HitPredict

Interactor 1: SNX2 (O60749)
Sorting nexin-2 (Transformation-related gene 9 protein) (TRG-9)
Gene: SNX2

Interactor 2: PGFRA (P16234)
Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)
Gene: PDGFRA

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	9819414
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0016020 - membrane GO:0032991 - protein-containing complex GO:0042803 - protein homodimerization activity
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 519 Hs			1 1089
+	Hs
		240337 SNX2_HUMAN (1-519): 5.7e-150: 440: 100.00		PGFRB_HUMAN (29-1089): 0: 650: 43.33
+	Hs
		307883 SNX4_HUMAN (93-513): 2.45e-73: 241: 18.20		PGFRA_HUMAN (1-1089): 0: 817: 100.00
+	Hs
		557294 SNX6_HUMAN (113-517): 4.05e-68: 226: 19.06		PGFRA_HUMAN (1-1089): 0: 817: 100.00
+	Hs
		452418 SNX1_HUMAN (2-519): 1.54e-123: 373: 59.32		PGFRB_HUMAN (29-1089): 0: 650: 43.33
+	Hs
		307878 SNX4_HUMAN (93-513): 2.45e-73: 241: 18.20		PGFRB_HUMAN (29-1089): 0: 650: 43.33
+	Hs
		240351 SNX2_HUMAN (1-519): 5.7e-150: 440: 100.00		FGFR4_HUMAN (3-221): 4.21e-22: 104: 8.36
+	Hs
		240358 SNX2_HUMAN (1-519): 5.7e-150: 440: 100.00		VGFR3_HUMAN (128-609): 7.49e-19: 94.9: 11.28
+	Hs
		240342 SNX2_HUMAN (1-519): 5.7e-150: 440: 100.00		FGFR1_HUMAN (3-177): 1.39e-14: 80.7: 10.71
+	Hs
		674416 SNX1_HUMAN (2-519): 1.54e-123: 373: 59.32		UFO_HUMAN (13-225): 2.38e-15: 83.4: 14.71
+	Hs
		507986 SNX1_HUMAN (2-519): 1.54e-123: 373: 59.32		FGFR1_HUMAN (3-177): 1.39e-14: 80.7: 10.71
+	Hs
		1081648 SNX7_HUMAN (112-512): 6e-80: 256: 22.44		NTRK3_HUMAN (28-227): 3.23e-13: 76.1: 9.01
+	Hs
		434311 SNX6_HUMAN (113-517): 4.05e-68: 226: 19.06		RET_HUMAN (573-690): 7.85e-22: 104: 43.22
+	Hs
		729384 SNX6_HUMAN (113-517): 4.05e-68: 226: 19.06		VGFR3_HUMAN (128-609): 7.49e-19: 94.9: 11.28
+	Hs
		508266 SNX6_HUMAN (113-517): 4.05e-68: 226: 19.06		FGFR1_HUMAN (3-177): 1.39e-14: 80.7: 10.71
+	Hs
		1081649 SNX6_HUMAN (113-517): 4.05e-68: 226: 19.06		NTRK3_HUMAN (28-227): 3.23e-13: 76.1: 9.01