Interactor 1: SNX2 (O60749)
Sorting nexin-2 (Transformation-related gene 9 protein) (TRG-9)
Gene: SNX2

Interactor 2: SNX5 (Q9Y5X3)
Sorting nexin-5
Gene: SNX5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.793

The method score is based on:

Property Details
Experiments 35271311, 21988832
Identification Methods affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains PX~PX, PX~Vps5, Vps5~Vps5
Common GO terms GO:0005768 - endosome
GO:0005829 - cytosol
GO:0006886 - intracellular protein transport
GO:0030904 - retromer complex
GO:0030905 - retromer, tubulation complex
and 3 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 519
Hs

1 404
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Dm
+ Ce
+ Hs
+ At
+ Hs
+ Ce
+ At
+ At
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024