HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: THIM (P42765)
3-ketoacyl-CoA thiolase, mitochondrial (EC 2.3.1.16) (Acetyl-CoA acetyltransferase) (EC 2.3.1.9) (Acetyl-CoA acyltransferase) (Acyl-CoA hydrolase, mitochondrial) (EC 3.1.2.-, EC 3.1.2.1, EC 3.1.2.2) (Beta-ketothiolase) (Mitochondrial 3-oxoacyl-CoA thiolase) (T1)
Gene: ACAA2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35509820, 35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 397
+	Hs
		242795 PRKN_HUMAN (1-465): 2.85e-136: 402: 100.00		THIC_HUMAN (7-394): 3.62e-171: 485: 42.56
+	Hs
		240782 PRKN_HUMAN (1-465): 2.85e-136: 402: 100.00		THIL_HUMAN (3-394): 5e-170: 483: 39.19
+	Hs
		241210 PRKN_HUMAN (1-465): 2.85e-136: 402: 100.00		ECHB_HUMAN (4-395): 1.44e-152: 441: 33.80
+	Sc
		509597 UBI4P_YEAST (1-229): 3.44e-60: 203: 18.72		ERG10_YEAST (5-394): 2.44e-165: 470: 37.12
+	At
		1167771 UBQ3_ARATH (1-77): 1.82e-30: 121: 31.17		ACCT2_ARATH (5-394): 5.23e-170: 482: 38.78
+	At
		1167642 UBQ3_ARATH (1-77): 1.82e-30: 121: 31.17		THIK2_ARATH (5-394): 1.44e-163: 468: 37.59