HitPredict

Interactor 1: TOM1 (O60784)
Target of Myb1 membrane trafficking protein (Target of Myb protein 1)
Gene: TOM1

Interactor 2: CLH1 (Q00610)
Clathrin heavy chain 1 (Clathrin heavy chain on chromosome 17) (CLH-17)
Gene: CLTC

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.680

Property	Details
Experiments	14563850, 34761192, 16412388, 15657082
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005768 - endosome GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016020 - membrane GO:0070062 - extracellular exosome
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 492 Hs			1 1675
+	Hs
		960857 TM1L2_HUMAN (1-492): 2.32e-147: 432: 61.45		CLH1_HUMAN (1-1675): 0: 3132: 100.00
+	Hs
		272801 TM1L1_HUMAN (7-487): 1.65e-105: 324: 29.66		CLH1_HUMAN (1-1675): 0: 3132: 100.00
+	Mm
		1148410 TM1L1_MOUSE (7-487): 2.09e-99: 308: 28.72		CLH1_MOUSE (1-1675): 0: 3131: 99.88
+	Hs
		960908 STAM1_HUMAN (1-477): 6.09e-92: 291: 19.27		CLH1_HUMAN (1-1675): 0: 3132: 100.00
+	Hs
		961013 GGA1_HUMAN (12-450): 6.7e-91: 291: 21.37		CLH1_HUMAN (1-1675): 0: 3132: 100.00
+	Hs
		961012 GGA2_HUMAN (5-456): 4.77e-89: 286: 19.01		CLH1_HUMAN (1-1675): 0: 3132: 100.00
+	Hs
		960999 GGA3_HUMAN (12-476): 3.9e-84: 276: 21.28		CLH1_HUMAN (1-1675): 0: 3132: 100.00
+	Mm
		1148412 HGS_MOUSE (10-478): 6.28e-80: 266: 17.87		CLH1_MOUSE (1-1675): 0: 3131: 99.88
+	Hs
		159961 HGS_HUMAN (10-465): 5.12e-76: 255: 17.90		CLH1_HUMAN (1-1675): 0: 3132: 100.00
+	Hs
		241158 TOM1_HUMAN (1-492): 5.19e-178: 510: 100.00		CLH2_HUMAN (1-1634): 0: 2869: 85.01
+	Hs
		863981 STAM1_HUMAN (1-477): 6.09e-92: 291: 19.27		CLH2_HUMAN (1-1634): 0: 2869: 85.01
+	Dm
		669650 Q9W329_DROME (10-485): 1.09e-63: 220: 16.42		CLH_DROME (1-1663): 0: 2911: 80.17
+	Dm
		669603 HRS_DROME (9-167): 2.37e-41: 159: 32.50		CLH_DROME (1-1663): 0: 2911: 80.17
+	Zm
		25357 C4J1G1_MAIZE (11-489): 1.87e-96: 304: 24.10		A0A1D6IQ85_MAIZE (6-1617): 0: 2658: 56.96
+	Ce
		712329 Q17796_CAEEL (10-152): 2.25e-41: 159: 32.17		CLH_CAEEL (5-1671): 0: 2799: 71.19
+	Sc
		604404 GGA2_YEAST (11-448): 3.49e-77: 254: 19.30		CLH_YEAST (5-1648): 0: 2443: 49.79
+	Sc
		604476 GGA1_YEAST (10-454): 4.3e-77: 253: 20.70		CLH_YEAST (5-1648): 0: 2443: 49.79