HitPredict

Interactor 1: H2B1K (O60814)
Histone H2B type 1-K (H2B K) (HIRA-interacting protein 1)
Gene: H2BC12

Interactor 2: KPCB (P05771)
Protein kinase C beta type (PKC-B) (PKC-beta) (EC 2.7.11.13)
Gene: PRKCB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 126 Hs			1 671
+	Hs
		408666 H2B1M_HUMAN (1-126): 4.46e-54: 167: 96.03		KPCB_HUMAN (1-671): 0: 774: 100.00
+	Hs
		408525 H2B1J_HUMAN (1-126): 6.13e-54: 166: 99.21		KPCB_HUMAN (1-671): 0: 774: 100.00
+	Hs
		408583 H2BFS_HUMAN (1-126): 9.81e-54: 166: 98.41		KPCB_HUMAN (1-671): 0: 774: 100.00
+	Hs
		408591 H2B1C_HUMAN (1-126): 1.07e-53: 166: 99.21		KPCB_HUMAN (1-671): 0: 774: 100.00
+	Hs
		408624 H2B2E_HUMAN (1-126): 5.55e-54: 166: 98.41		KPCB_HUMAN (1-671): 0: 774: 100.00
+	Hs
		408565 H2B1B_HUMAN (1-126): 1.52e-53: 165: 96.83		KPCB_HUMAN (1-671): 0: 774: 100.00
+	Hs
		408664 H2B1N_HUMAN (1-126): 2.97e-53: 165: 98.41		KPCB_HUMAN (1-671): 0: 774: 100.00
+	Hs
		408585 H2B1D_HUMAN (1-126): 3.17e-53: 164: 98.41		KPCB_HUMAN (1-671): 0: 774: 100.00
+	Hs
		408667 H2B1L_HUMAN (1-126): 2.18e-52: 163: 97.62		KPCB_HUMAN (1-671): 0: 774: 100.00
+	Mm
		682111 H2B2B_MOUSE (1-126): 2.19e-54: 168: 97.62		AKT1_MOUSE (239-665): 1.05e-159: 470: 37.33
+	Hs
		617926 H2B1O_HUMAN (1-126): 2.88e-54: 167: 97.62		AKT1_HUMAN (239-665): 2.36e-159: 469: 37.33
+	Hs
		617927 H2B1O_HUMAN (1-126): 2.88e-54: 167: 97.62		AKT2_HUMAN (237-665): 2.34e-159: 469: 37.87
+	Mm
		682113 H2B1C_MOUSE (1-126): 1.07e-53: 166: 99.21		AKT1_MOUSE (239-665): 1.05e-159: 470: 37.33
+	Hs
		420806 H2B1J_HUMAN (1-126): 6.13e-54: 166: 99.21		AKT1_HUMAN (239-665): 2.36e-159: 469: 37.33
+	Hs
		420807 H2B1J_HUMAN (1-126): 6.13e-54: 166: 99.21		AKT2_HUMAN (237-665): 2.34e-159: 469: 37.87
+	Hs
		681878 H2B2E_HUMAN (1-126): 5.55e-54: 166: 98.41		AKT1_HUMAN (239-665): 2.36e-159: 469: 37.33
+	Hs
		682181 H2B2E_HUMAN (1-126): 5.55e-54: 166: 98.41		AKT2_HUMAN (237-665): 2.34e-159: 469: 37.87
+	Hs
		681686 H2B1B_HUMAN (1-126): 1.52e-53: 165: 96.83		AKT1_HUMAN (239-665): 2.36e-159: 469: 37.33
+	Hs
		682137 H2B1B_HUMAN (1-126): 1.52e-53: 165: 96.83		AKT2_HUMAN (237-665): 2.34e-159: 469: 37.87
+	Hs
		241512 H2B1K_HUMAN (1-126): 1.2e-53: 166: 100.00		KPCD_HUMAN (6-167): 1.49e-54: 199: 40.83