HitPredict

Interactor 1: H2B1K (O60814)
Histone H2B type 1-K (H2B K) (HIRA-interacting protein 1)
Gene: H2BC12

Interactor 2: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35063084
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 126 Hs			1 758
+	Hs
		497505 H2B1M_HUMAN (1-126): 4.46e-54: 167: 96.03		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		420796 H2B1J_HUMAN (1-126): 6.13e-54: 166: 99.21		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		497113 H2B2E_HUMAN (1-126): 5.55e-54: 166: 98.41		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		497292 H2B3B_HUMAN (1-126): 8.48e-52: 161: 94.44		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		241456 H2B1K_HUMAN (1-126): 1.2e-53: 166: 100.00		MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56
+	Hs
		653955 H2B1C_HUMAN (1-126): 1.07e-53: 166: 99.21		MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56
+	Hs
		653945 H2B1D_HUMAN (1-126): 3.17e-53: 164: 98.41		MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56
+	Hs
		654046 H2B1L_HUMAN (1-126): 2.18e-52: 163: 97.62		MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56
+	Hs
		1056847 H2B2E_HUMAN (1-126): 5.55e-54: 166: 98.41		MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57
+	Hs
		1056919 H2B1H_HUMAN (1-126): 5.43e-54: 166: 98.41		MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57
+	Hs
		918364 H2B1C_HUMAN (1-126): 1.07e-53: 166: 99.21		MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57
+	Hs
		707631 H2B1B_HUMAN (1-126): 1.52e-53: 165: 96.83		MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57
+	Hs
		152598 H2B1B_HUMAN (1-126): 1.52e-53: 165: 96.83		KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55
+	Hs
		1087210 H2B2E_HUMAN (1-126): 5.55e-54: 166: 98.41		SRCAP_HUMAN (2-474): 1.09e-12: 74.3: 9.83
+	Hs
		918462 H2B1C_HUMAN (1-126): 1.07e-53: 166: 99.21		SRCAP_HUMAN (2-474): 1.09e-12: 74.3: 9.83
+	Hs
		707663 H2B1B_HUMAN (1-126): 1.52e-53: 165: 96.83		SRCAP_HUMAN (2-474): 1.09e-12: 74.3: 9.83
+	Hs
		918533 H2B1C_HUMAN (1-126): 1.07e-53: 166: 99.21		KMT2C_HUMAN (83-649): 6.28e-09: 61.8: 12.91
+	Hs
		1274405 H2B1H_HUMAN (1-126): 5.43e-54: 166: 98.41		ZN469_HUMAN (7-623): 9.52e-09: 61.2: 10.94
+	Hs
		707690 H2B1B_HUMAN (1-126): 1.52e-53: 165: 96.83		KMT2C_HUMAN (83-649): 6.28e-09: 61.8: 12.91
+	Hs
		1295175 H2B1L_HUMAN (1-126): 2.18e-52: 163: 97.62		ZN469_HUMAN (7-623): 9.52e-09: 61.2: 10.94